4-(3-Hydroxyphenyl)benzonitrile
4-(3-Hydroxyphenyl)benzonitrile (CAS: 486455-27-0, C13H9NO) is a fine chemical building block with a molecular weight of 195.22 g/mol. This organic compound, featuring both hydroxyl and nitrile functional groups on a biphenyl core, is primarily utilised in chemical synthesis and organic building block applications. Supplied at a purity of 97%, it serves as a key intermediate in the development of more complex molecules for research and development purposes.
- IUPAC
- 3′-Hydroxy-[1,1′-biphenyl]-4-carbonitrile,3′-Hydroxybiphenyl-4-carbonitrile
- Synonyms
- 3′-Hydroxy-[1,1′-biphenyl]-4-carbonitrile, 3′-Hydroxybiphenyl-4-carbonitrile

Organic Synthesis Intermediate
This compound acts as a versatile intermediate in organic synthesis. Its functional groups allow for diverse chemical transformations, enabling the construction of intricate molecular architectures.
Pharmaceutical Research
As a building block, 4-(3-Hydroxyphenyl)benzonitrile may be employed in the early stages of pharmaceutical research for the synthesis of potential drug candidates or biologically active molecules.
Materials Science
The unique structure of this molecule could lend itself to applications in materials science, potentially in the development of novel polymers or functional materials.
| Molecular weight | 195.22 |
|---|---|
| Empirical formula | C13H9NO |
| Assay | 97% |
| Melting point | 160-164 °C(lit.) |


Hazard statements
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H318Causes serious eye damage
- H332Harmful if inhaled
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Transport (UN / ADR) | UN 3077 9 / PGIII |
| Water hazard class (WGK, DE) | 2 |
| Hazard codes (EU) | Xn,N |
| Risk statements (R) | 20/21/22-41-51/53 |
| Safety statements (S) | 26-36/37/39-61 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-(3-Hydroxyphenyl)benzonitrile used for?
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4-(3-Hydroxyphenyl)benzonitrile is primarily used as a building block in organic synthesis and may find application in pharmaceutical research and materials science.
What is the CAS number and molecular formula for 4-(3-Hydroxyphenyl)benzonitrile?
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The CAS number is 486455-27-0 and the molecular formula is C13H9NO.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-(3-Hydroxyphenyl)benzonitrile with an assay of 97%. We do not represent this product as USP, BP, EP, or any pharmacopoeia grade unless explicitly stated otherwise.
How should 4-(3-Hydroxyphenyl)benzonitrile be handled safely?
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4-(3-Hydroxyphenyl)benzonitrile is classified as Danger, with hazards including H302 (Harmful if swallowed), H312 (Harmful in contact with skin), H318 (Causes serious eye damage), and H332 (Harmful if inhaled). Appropriate personal protective equipment, including a dust mask type N95 (US), eyeshields, and gloves, should be worn. Handle in a well-ventilated area.
How is 4-(3-Hydroxyphenyl)benzonitrile packed and exported?
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This chemical is shipped and exported according to regulations, including UN 3077 classification for transport. Packaging is designed to maintain product integrity and comply with international shipping standards.
How can I request a sample or quote for 4-(3-Hydroxyphenyl)benzonitrile?
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To request a sample or a quote, please contact the Tech Serve Solutions sales team through our website or by phone. Please reference the product name and CAS number.
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