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4-(2-Aminoethyl)benzenesulfonyl fluoride hydrochloride

CAS 30827-99-7C8H10FNO2S · HClBiochemicals & Reagents

4-(2-Aminoethyl)benzenesulfonyl fluoride hydrochloride (CAS: 30827-99-7; Formula: C8H10FNO2S · HCl; MW: 239.69) is a PREMIUM grade chemical reagent. It is a potent inhibitor of serine proteases, including chymotrypsin. This compound is valuable in biochemical research, particularly for studying enzyme mechanisms and as a protease inhibitor in cell lysis protocols. Its reactivity makes it useful in protein chemistry and for stabilising protein samples.

IUPAC
AEBSF
Synonyms
AEBSF
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4-(2-Aminoethyl)benzenesulfonyl fluoride hydrochloride (C8H10FNO2S · HCl) — chemical structure, CAS 30827-99-7; Life Science, fine chemical supplied by Tech Serve Solutions
A to CA-AMBioactive Small MoleculesBiochemicals and ReagentsCell BiologyChymotrypsinalpha-Core BioreagentsEnzyme InhibitorsEnzyme Inhibitors by Enzyme
01 /Applications

Serine Protease Inhibition

Utilised as a broad-spectrum inhibitor of serine proteases, notably chymotrypsin. It is recommended for use at concentrations of 0.1-1 mM to block enzymatic activity in biochemical assays and experiments.

Biochemical Research Tool

Serves as a crucial reagent in biochemical research for investigating enzyme kinetics and mechanisms. Its ability to inhibit proteolytic enzymes aids in the study of protein function and degradation pathways.

Cell Lysis and Protein Stabilisation

Incorporated into cell lysis buffers to prevent protein degradation by endogenous proteases. This helps maintain the integrity of target proteins during sample preparation and analysis.

02 /Properties
Molecular weight239.69
Empirical formulaC8H10FNO2S · HCl
Assay≥97%
SolubilityH2O: soluble50 mg/mL (stable for up to six months if stored refrigerated at a pH of less than 7. If a pH of greater than 7 is required, pH adjustment should be made just prior to use.)
Storage temperature−20°C
ApplicationRecommended concentrations for use are 0.1-1 mM.
Melting point~183 °C
03 /Safety & handling
GHS hazard pictogram: Corrosive (GHS05)
Corrosive
Danger

Hazard statements

  • H314Causes severe skin burns and eye damage

Precautionary statements

  • P280Wear protective gloves, clothing and eye/face protection
  • P305IF IN EYES
  • P310Immediately call a POISON CENTER or doctor
Transport (UN / ADR)UN 3261 8 / PGII
Water hazard class (WGK, DE)3
Hazard codes (EU)C
Risk statements (R)34
Safety statements (S)26-36/37/39-45

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
30827-99-7
MDL number
MFCD00132962
PubChem substance
24278240
Beilstein registry
7604627
05 /Additional specifications
Quality LevelPREMIUM
06 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

07 /Frequently asked questions

What is 4-(2-Aminoethyl)benzenesulfonyl fluoride hydrochloride used for?

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4-(2-Aminoethyl)benzenesulfonyl fluoride hydrochloride (CAS: 30827-99-7) is primarily used as a serine protease inhibitor, particularly effective against chymotrypsin, in biochemical research and for protein stabilisation during cell lysis.

What is the CAS number and formula for 4-(2-Aminoethyl)benzenesulfonyl fluoride hydrochloride?

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The CAS number is 30827-99-7, and the empirical formula is C8H10FNO2S · HCl.

What grade and purity does Tech Serve Solutions supply?

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Tech Serve Solutions supplies this compound at a PREMIUM quality level with an assay of ≥97%. We do not represent this product as meeting USP, BP, or EP pharmacopoeial standards.

How should 4-(2-Aminoethyl)benzenesulfonyl fluoride hydrochloride be handled safely?

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This compound is classified as Danger with hazard statement H314 (Causes severe skin burns and eye damage). Handle with appropriate personal protective equipment, including gloves, eye protection, and protective clothing. Ensure good ventilation and avoid breathing dust. In case of contact, rinse cautiously with water for several minutes and seek immediate medical attention.

How is this chemical packed and shipped?

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This chemical is shipped as a hazardous material under UN 3261, Class 8, Packing Group II. Packaging and shipping adhere to international regulations for dangerous goods.

How can I request a quote or sample?

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To request a quote or a sample, please contact our sales department via the website or by phone, providing the product name and CAS number (30827-99-7).

Need 4-(2-Aminoethyl)benzenesulfonyl fluoride hydrochloride in a specific grade or volume?