4-(2-Aminoethyl)benzenesulfonyl fluoride hydrochloride
4-(2-Aminoethyl)benzenesulfonyl fluoride hydrochloride (CAS: 30827-99-7; Formula: C8H10FNO2S · HCl; MW: 239.69) is a PREMIUM grade chemical reagent. It is a potent inhibitor of serine proteases, including chymotrypsin. This compound is valuable in biochemical research, particularly for studying enzyme mechanisms and as a protease inhibitor in cell lysis protocols. Its reactivity makes it useful in protein chemistry and for stabilising protein samples.
- IUPAC
- AEBSF
- Synonyms
- AEBSF

Serine Protease Inhibition
Utilised as a broad-spectrum inhibitor of serine proteases, notably chymotrypsin. It is recommended for use at concentrations of 0.1-1 mM to block enzymatic activity in biochemical assays and experiments.
Biochemical Research Tool
Serves as a crucial reagent in biochemical research for investigating enzyme kinetics and mechanisms. Its ability to inhibit proteolytic enzymes aids in the study of protein function and degradation pathways.
Cell Lysis and Protein Stabilisation
Incorporated into cell lysis buffers to prevent protein degradation by endogenous proteases. This helps maintain the integrity of target proteins during sample preparation and analysis.
| Molecular weight | 239.69 |
|---|---|
| Empirical formula | C8H10FNO2S · HCl |
| Assay | ≥97% |
| Solubility | H2O: soluble50 mg/mL (stable for up to six months if stored refrigerated at a pH of less than 7. If a pH of greater than 7 is required, pH adjustment should be made just prior to use.) |
| Storage temperature | −20°C |
| Application | Recommended concentrations for use are 0.1-1 mM. |
| Melting point | ~183 °C |

Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Transport (UN / ADR) | UN 3261 8 / PGII |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Quality Level | PREMIUM |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-(2-Aminoethyl)benzenesulfonyl fluoride hydrochloride used for?
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4-(2-Aminoethyl)benzenesulfonyl fluoride hydrochloride (CAS: 30827-99-7) is primarily used as a serine protease inhibitor, particularly effective against chymotrypsin, in biochemical research and for protein stabilisation during cell lysis.
What is the CAS number and formula for 4-(2-Aminoethyl)benzenesulfonyl fluoride hydrochloride?
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The CAS number is 30827-99-7, and the empirical formula is C8H10FNO2S · HCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this compound at a PREMIUM quality level with an assay of ≥97%. We do not represent this product as meeting USP, BP, or EP pharmacopoeial standards.
How should 4-(2-Aminoethyl)benzenesulfonyl fluoride hydrochloride be handled safely?
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This compound is classified as Danger with hazard statement H314 (Causes severe skin burns and eye damage). Handle with appropriate personal protective equipment, including gloves, eye protection, and protective clothing. Ensure good ventilation and avoid breathing dust. In case of contact, rinse cautiously with water for several minutes and seek immediate medical attention.
How is this chemical packed and shipped?
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This chemical is shipped as a hazardous material under UN 3261, Class 8, Packing Group II. Packaging and shipping adhere to international regulations for dangerous goods.
How can I request a quote or sample?
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To request a quote or a sample, please contact our sales department via the website or by phone, providing the product name and CAS number (30827-99-7).
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