3-(Tritylthio)propionic acid
3-(Tritylthio)propionic acid (CAS: 27144-18-9) is a valuable organic compound with the linear formula (C6H5)3CSCH2CH2COOH and a molecular weight of 348.46 g/mol. This carboxylic acid derivative serves as a versatile building block in chemical synthesis. It is particularly useful in organic chemistry for introducing specific functional groups and participating in reactions requiring a protected thiol or a carboxylic acid moiety. Its applications span various research and development fields.

Organic Synthesis Intermediate
Serves as a key intermediate in the synthesis of complex organic molecules. The tritylthio group offers a readily cleavable protecting group for thiols, while the propionic acid moiety allows for further functionalization.
Pharmaceutical Research
Utilised in the development of novel pharmaceutical compounds and drug discovery efforts, where precise molecular architecture is critical. It can be incorporated into potential therapeutic agents.
Materials Science
May be employed in the synthesis of specialised polymers or functionalised materials, leveraging its unique combination of a bulky protecting group and an acidic functionality.
Chemical Reagent
Functions as a reagent in laboratory settings for various chemical transformations and research projects requiring its specific structural features.
| Molecular weight | 348.46 |
|---|---|
| Linear formula | (C6H5)3CSCH2CH2COOH |
| Assay | ≥97.0% (T) |

Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
- H413May cause long-lasting harmful effects to aquatic life
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-(Tritylthio)propionic acid used for?
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3-(Tritylthio)propionic acid is used as a versatile building block in organic synthesis, particularly in pharmaceutical research and materials science, for introducing specific functional groups and as a protected thiol derivative.
What is the CAS number and chemical formula for 3-(Tritylthio)propionic acid?
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The CAS number is 27144-18-9 and the linear formula is (C6H5)3CSCH2CH2COOH.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 3-(Tritylthio)propionic acid with an assay of ≥97.0% (T). This product is suitable for research and laboratory use. TSS does not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should 3-(Tritylthio)propionic acid be handled?
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Handle with appropriate personal protective equipment, including a dust mask (type N95 US), eyeshields, and gloves. Avoid breathing dust and ensure adequate ventilation. Refer to the Safety Data Sheet for comprehensive handling information.
Does TSS export 3-(Tritylthio)propionic acid?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including 3-(Tritylthio)propionic acid, and can fulfil export requirements.
How can I request a sample or quote for 3-(Tritylthio)propionic acid?
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To request a sample or a quote, please use the contact form on our website or reach out to our sales team, specifying the product name and CAS number.
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