(−)-Guaiol

CAS 489-86-1C15H26OChemical Synthesis

(−)-Guaiol (CAS 489-86-1), with the molecular formula C15H26O and a molecular weight of 222.37 g/mol, is a bicyclic sesquiterpenoid alcohol. This chiral compound is primarily recognised for its utility as a building block in organic synthesis, particularly in asymmetric synthesis due to its defined stereochemistry. It serves as a valuable intermediate for the construction of more complex molecular architectures in research and development settings.

IUPAC: (3R,6S,10S)-6,10,α,α-Tetramethylbicyclo[5.3.0]dec-1(7)-ene-3-methanol

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(−)-Guaiol (C15H26O) — chemical structure, CAS 489-86-1; Chemistry, fine chemical supplied by Tech Serve Solutions

AlcoholsAsymmetric SynthesisChemical SynthesisChiral Building BlocksOrganic Building Blocks

01 /Applications

Chiral Building Block

Its inherent chirality makes (−)-Guaiol an attractive starting material for the enantioselective synthesis of complex organic molecules. It is employed in constructing stereodefined fragments for natural product synthesis and medicinal chemistry research.

Asymmetric Synthesis

The specific stereochemical configuration of (−)-Guaiol allows it to be used as a chiral auxiliary or precursor in asymmetric synthesis. This enables the stereoselective creation of new chiral centres in target molecules.

Organic Synthesis Intermediate

As a versatile alcohol, (−)-Guaiol can undergo various chemical transformations, serving as a key intermediate in multi-step synthetic pathways. Its bicyclic structure provides a rigid scaffold for further functionalization.

02 /Properties

Molecular weight	222.37
Empirical formula	C15H26O
Assay	≥98.0% (sum of enantiomers, HPLC)
Optical activity	[α]20/D −28±2°, c = 4% in ethanol
Storage temperature	2-8°C
Melting point	91-93 °C(lit.)91-93 °C

03 /Safety & handling

Protective equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)	3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

489-86-1

MDL number

MFCD00043336

Beilstein registry

2047993

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is (−)-Guaiol used for?

(−)-Guaiol is used as a chiral building block and intermediate in organic synthesis, particularly in asymmetric synthesis for research and development.

What is the CAS number and formula for (−)-Guaiol?

The CAS number for (−)-Guaiol is 489-86-1, and its molecular formula is C15H26O.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies (−)-Guaiol with an assay of ≥98.0% (sum of enantiomers, HPLC). We do not represent this product as USP, BP, EP, or other pharmacopoeia grades.

What are the safety and handling requirements for (−)-Guaiol?

Handling (−)-Guaiol requires appropriate personal protective equipment, including eyeshields and gloves. It has a WGK Germany rating of 3, indicating a high hazard level. Ensure adequate ventilation and use a suitable respirator filter (type N95 or P1).

How is (−)-Guaiol shipped or exported by TSS?

TSS can export chemicals globally. Specific packaging and shipping details for (−)-Guaiol are available upon request, adhering to all relevant regulations.

How can I request a sample or quote for (−)-Guaiol?

To request a sample or quote for (−)-Guaiol, please contact our sales department via the website or direct email, providing your specific requirements.