3-Thiophenemalonic acid
3-Thiophenemalonic acid (CAS: 21080-92-2; Formula: C7H6O4S) is a chemical compound with a molecular weight of 186.19 g/mol. It is recognised as a dicarboxylic acid derivative of thiophene. This compound finds utility as a building block in organic synthesis, particularly in the development of novel materials and pharmaceutical intermediates. Its structure lends itself to polymerisation and functionalisation, making it a valuable reagent in materials science and polymer chemistry research.
- IUPAC
- α-Carboxythiophene-3-acetic acid,(3-Thienyl)malonic acid
- Synonyms
- (3-Thienyl)malonic acidα-Carboxythiophene-3-acetic acid

Organic Synthesis Intermediate
3-Thiophenemalonic acid serves as a versatile intermediate in complex organic syntheses. Its reactive carboxylic acid groups allow for various derivatisations, enabling the construction of more elaborate molecular architectures.
Monomer for Polymer Science
As a functionalised monomer, this compound can be incorporated into polymer backbones. This is particularly relevant in materials science for creating polymers with tailored electronic or optical properties derived from the thiophene moiety.
Pharmaceutical Research
The thiophene ring system is present in various biologically active molecules. 3-Thiophenemalonic acid can act as a precursor for synthesising potential pharmaceutical agents or drug candidates in early-stage research.
Materials Science
The unique structure of 3-Thiophenemalonic acid makes it a candidate for developing advanced materials. It can be used in the synthesis of functional organic materials with applications in electronics or optoelectronics.
| Molecular weight | 186.19 |
|---|---|
| Empirical formula | C7H6O4S |
| Assay | 97% |
| Melting point | 139 °C (dec.)(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-Thiophenemalonic acid used for?
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3-Thiophenemalonic acid is primarily used as an intermediate in organic synthesis, a monomer in polymer science, and in materials science research. It can also serve as a building block in the development of pharmaceutical intermediates.
What is the CAS number and formula for 3-Thiophenemalonic acid?
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The CAS number is 21080-92-2 and the empirical formula is C7H6O4S.
What grade and purity does Tech Serve Solutions supply for 3-Thiophenemalonic acid?
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Tech Serve Solutions supplies 3-Thiophenemalonic acid with an assay of 97%. We do not represent this product as USP, BP, or EP grade.
How should 3-Thiophenemalonic acid be handled safely?
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Handling requires appropriate personal protective equipment, including a dust mask type N95 (US), eyeshields, and gloves. Avoid breathing dust and ensure adequate ventilation. Refer to the Safety Data Sheet for comprehensive information.
Is 3-Thiophenemalonic acid a controlled substance?
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The provided data does not indicate that 3-Thiophenemalonic acid is a controlled substance.
How is 3-Thiophenemalonic acid typically shipped and exported?
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Tech Serve Solutions is a global supplier and exporter of fine chemicals, ensuring that products are packaged and shipped in compliance with international regulations for chemical transport.
How can I request a sample or quote for 3-Thiophenemalonic acid?
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Please contact our sales department through the website or direct inquiry channels to request a sample or a formal quotation for 3-Thiophenemalonic acid.
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