3-Nitrophenylboronic acid
3-Nitrophenylboronic acid (CAS: 13331-27-6; Formula: O2NC6H4B(OH)2; MW: 166.93) is a key organometallic reagent widely employed in chemical synthesis. It serves as a valuable intermediate, notably catalyzing the ene carbocyclization of acetylenic dicarbonyl compounds. Tech Serve Solutions supplies this compound with a minimum assay of 97%, ensuring reliable performance in research and development applications.
- IUPAC
- 3-Nitrobenzeneboronic acid,m-Nitrobenzeneboronic acid,m-Nitrophenylboronic acid,NSC 401539,NSC 59739
- Synonyms
- 3-Nitrobenzeneboronic acidm-Nitrobenzeneboronic acidm-Nitrophenylboronic acidNSC 401539NSC 59739
Catalysis in Organic Synthesis
3-Nitrophenylboronic acid functions as a catalyst, specifically noted for its role in the ene carbocyclization of acetylenic dicarbonyl compounds. This application is crucial for constructing complex molecular architectures in organic chemistry research.
Building Block for Complex Molecules
As an aryl boronic acid derivative, this compound is a versatile building block in cross-coupling reactions, enabling the synthesis of substituted aromatic compounds. Its nitro group offers further potential for functional group transformations.
Intermediate in Pharmaceutical Research
Boronic acids are integral to medicinal chemistry. 3-Nitrophenylboronic acid can serve as an intermediate in the synthesis of novel pharmaceutical agents, where precise structural modifications are required.
| Molecular weight | 166.93 |
|---|---|
| Linear formula | O2NC6H4B(OH)2 |
| Assay | ≥97% |
| Application | Catalyzes ene carbocyclization of acetylenic dicarbonyl compounds8 |
| Melting point | 284-285 °C (dec.)(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-Nitrophenylboronic acid primarily used for?
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3-Nitrophenylboronic acid is primarily used as a catalyst in organic synthesis, notably for the ene carbocyclization of acetylenic dicarbonyl compounds, and as a versatile building block for constructing complex organic molecules.
What is the CAS number and chemical formula for 3-Nitrophenylboronic acid?
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The CAS number for 3-Nitrophenylboronic acid is 13331-27-6, and its chemical formula is O2NC6H4B(OH)2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 3-Nitrophenylboronic acid with a minimum assay of 97%. This product is intended for research and laboratory use and is not represented as USP, BP, EP, or any other pharmacopoeial grade.
What are the safety and handling precautions for 3-Nitrophenylboronic acid?
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3-Nitrophenylboronic acid is a warning chemical (GHS07) with hazard statements H315, H319, and H335, indicating it causes skin irritation, serious eye irritation, and may cause respiratory irritation. Appropriate personal protective equipment, including a dust mask (N95), eyeshields, and gloves, should be used. Handle in a well-ventilated area.
How is 3-Nitrophenylboronic acid packed, shipped, and exported?
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Tech Serve Solutions professionally packs, ships, and exports 3-Nitrophenylboronic acid globally, adhering to all necessary regulations for chemical transport.
How can I request a quote or sample of 3-Nitrophenylboronic acid?
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To request a quote or sample of 3-Nitrophenylboronic acid, please contact our sales team through the website or by phone, providing your specific requirements.
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