3-Methylbenzofuran-2-carbonyl chloride
3-Methylbenzofuran-2-carbonyl chloride (CAS: 2256-86-2; Formula: C10H7ClO2; MW: 194.61 g/mol) is a valuable benzofuran derivative and heterocyclic building block. This reactive acyl chloride is primarily employed in organic synthesis for the introduction of the 3-methylbenzofuran-2-carbonyl moiety into various molecules. Its utility is significant in the development of novel chemical entities and intermediates across research and industrial sectors.

Organic Synthesis Intermediate
Serves as a key intermediate in the synthesis of more complex organic molecules. Its acyl chloride functionality readily participates in acylation reactions with nucleophiles like alcohols and amines.
Heterocyclic Chemistry Research
A useful building block for constructing diverse heterocyclic systems, particularly those incorporating the benzofuran scaffold. It enables the synthesis of compounds with potential biological or material properties.
Pharmaceutical Intermediate Development
Employed in the exploration and synthesis pathways for novel pharmaceutical candidates. The benzofuran core is present in various biologically active compounds, making this a relevant starting material.
| Molecular weight | 194.61 |
|---|---|
| Empirical formula | C10H7ClO2 |
| Assay | 97% |
| Melting point | 72-77 °C(lit.) |

Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 3261 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-Methylbenzofuran-2-carbonyl chloride used for?
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3-Methylbenzofuran-2-carbonyl chloride is used as an intermediate in organic synthesis, particularly for introducing the 3-methylbenzofuran-2-carbonyl group into other molecules. It is valuable in heterocyclic chemistry and pharmaceutical intermediate development.
What are the CAS number and chemical formula?
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The CAS number for 3-Methylbenzofuran-2-carbonyl chloride is 2256-86-2, and its chemical formula is C10H7ClO2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 3-Methylbenzofuran-2-carbonyl chloride with a minimum assay of 97%. This product is supplied for laboratory and commercial use and is not represented as USP, BP, EP, or pharmacopoeia grade.
What are the primary safety hazards associated with this chemical?
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This compound is classified as Danger (GHS05) and causes severe skin burns and eye damage (H314). Appropriate personal protective equipment, including eye protection, gloves, and respiratory protection, must be used when handling. Refer to the safety data sheet for comprehensive handling information.
How is this product packed and shipped?
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This chemical is typically packed in appropriate containers suitable for hazardous materials and shipped in accordance with international regulations for dangerous goods (UN 3261, Class 8, Packing Group II).
How can I request a quote or sample?
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To request a quote or sample of 3-Methylbenzofuran-2-carbonyl chloride, please contact our sales department through the website or by phone, providing your specific requirements.
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