3-Methyl-1-butanethiol
3-Methyl-1-butanethiol (CAS 541-31-1), with the linear formula (CH3)2CHCH2CH2SH and a molecular weight of 104.21 g/mol, is an organic compound belonging to the thiol family. This volatile liquid, characterised by its strong odour, is primarily utilised as a chemical building block and in materials science applications, particularly in the synthesis of nanoparticles. Tech Serve Solutions supplies this chemical with a purity of 97%.
- IUPAC
- Isoamyl mercaptan
- Synonyms
- Isoamyl mercaptan

Nanoparticle Synthesis
3-Methyl-1-butanethiol serves as an organic capping agent in the synthesis of gold nanoparticles. Its application is crucial for controlling nanoparticle size, for instance, in the production of 5 nm gold nanoparticles.
Chemical Synthesis Building Block
As an alkyl thiol, this compound is a valuable building block in organic synthesis. It can be incorporated into more complex molecules, enabling the creation of novel chemical structures for research and development.
Materials Science
The unique properties of thiols, including 3-Methyl-1-butanethiol, make them useful in materials science. They can be employed in self-assembly processes for surface modification and the development of advanced materials.
| Molecular weight | 104.21 |
|---|---|
| Linear formula | (CH3)2CHCH2CH2SH |
| Assay | 97% |
| Boiling point | 117-118 °C(lit.) |
| Density | 0.835 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.4432(lit.) |
| Vapour pressure | 41.4 mmHg (37.7 °C) |
| Application | 3-Methyl-1-butanethiol has been used as an organic clapping layer in the synthesis of monolayer-capped 5 nm gold nanoparticles1. |


Hazard statements
- H225Highly flammable liquid and vapour
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 18 °C / 64.4 °F |
| Transport (UN / ADR) | UN 1228 3/PG 2 |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,Xi |
| Risk statements (R) | 11-36/37/38 |
| Safety statements (S) | 16-26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-Methyl-1-butanethiol used for?
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3-Methyl-1-butanethiol is used as a chemical building block in organic synthesis and in materials science, notably as an organic capping layer in the synthesis of gold nanoparticles.
What are the CAS number and formula for 3-Methyl-1-butanethiol?
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The CAS number for 3-Methyl-1-butanethiol is 541-31-1, and its linear formula is (CH3)2CHCH2CH2SH.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 3-Methyl-1-butanethiol with a purity of 97%. This product is intended for research and laboratory use and is not represented as USP, BP, or EP grade.
How should 3-Methyl-1-butanethiol be handled safely?
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3-Methyl-1-butanethiol is a highly flammable liquid and vapour (H225) and causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). It should be handled in a well-ventilated area, away from ignition sources, using appropriate personal protective equipment including eyeshields, gloves, and respiratory protection.
How is 3-Methyl-1-butanethiol packed and shipped?
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As a specialist global supplier, Tech Serve Solutions exports 3-Methyl-1-butanethiol, adhering to all necessary shipping and safety regulations for hazardous materials.
How can I request a sample or quote for 3-Methyl-1-butanethiol?
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To request a sample or quote for 3-Methyl-1-butanethiol, please contact our sales team through the TSS website or via direct inquiry.
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