3-Methoxyphenethylamine
3-Methoxyphenethylamine (CAS: 2039-67-0), with the molecular formula C9H13NO, is a valuable organic building block. This compound, characterized by its amine and methoxy-substituted phenyl group, serves as a key intermediate in chemical synthesis. It is utilized in specialized reactions, including the Pictet-Spengler reaction and palladium-catalyzed coupling for the formation of heterocyclic compounds, contributing to advanced research and development.
- IUPAC
- 2-(3-Methoxyphenyl)ethylamine
Pictet-Spengler Reaction
3-Methoxyphenethylamine is employed as a reactant in the perfluorooctanesulfonic acid catalyzed Pictet-Spengler reaction, a key transformation in organic synthesis for forming cyclic structures.
Synthesis of 1,3-Oxazepines
This amine derivative has been utilized in the synthesis of 1,3-oxazepines through palladium-catalyzed intramolecular coupling reactions, demonstrating its utility in constructing complex heterocyclic systems.
Organic Building Block
As a versatile organic building block, 3-Methoxyphenethylamine is integral to the synthesis of more complex molecules in research and development settings across various chemical disciplines.
| Molecular weight | 151.21 |
|---|---|
| Linear formula | CH3OC6H4CH2CH2NH2 |
| Assay | 97% |
| Boiling point | 118-119 °C/6 mmHg(lit.) |
| Density | 1.038 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.538(lit.) |
| Application | 3-Methoxyphenethylamine was used in the perfluorooctanesulfonic acid catalyzed Pictet-Spengler reaction1. It was also used in the synthesis of 1,3-oxazepines via palladium-catalyzed intramolecular coupling2. |
Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 110 °C / 230 °F |
| Transport (UN / ADR) | UN 2735 8/PG 3 |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-Methoxyphenethylamine primarily used for?
+
3-Methoxyphenethylamine is primarily used as a building block and intermediate in chemical synthesis, notably in reactions like the Pictet-Spengler reaction and the synthesis of heterocyclic compounds such as 1,3-oxazepines.
What is the CAS number and chemical formula for 3-Methoxyphenethylamine?
+
The CAS number for 3-Methoxyphenethylamine is 2039-67-0, and its chemical formula is C9H13NO (CH3OC6H4CH2CH2NH2).
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies 3-Methoxyphenethylamine with an assay of 97%. This is a technical/research grade material, and TSS does not represent it as USP, BP, or EP grade.
How should 3-Methoxyphenethylamine be handled safely?
+
3-Methoxyphenethylamine is classified as corrosive. Handling requires appropriate personal protective equipment, including gloves, goggles, a face shield, and a suitable respirator. Avoid contact with skin and eyes, and ensure good ventilation. Refer to the safety data sheet for detailed handling procedures.
How is 3-Methoxyphenethylamine packed and shipped?
+
3-Methoxyphenethylamine is packed and shipped in compliance with relevant regulations for hazardous materials, including UN 2735 classification for transport. TSS exports globally, adhering to international shipping standards.
How can I request a quote or sample for 3-Methoxyphenethylamine?
+
To request a quote or sample for 3-Methoxyphenethylamine, please contact the TSS sales team through our website or by phone, providing your specific requirements.
▶ Related products
1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis
1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis