3-Methoxybenzylmagnesium chloride solution
3-Methoxybenzylmagnesium chloride solution (CAS: 26905-40-8) is a valuable organometallic reagent with the linear formula H₃COC₆H₄CH₂MgCl and a molecular weight of 180.91 g/mol. Supplied as a 0.25 M solution in THF, this Grignard reagent is highly reactive, often used in organic synthesis for introducing the 3-methoxybenzyl group. Its applications span the creation of complex organic molecules within pharmaceutical and fine chemical research and development.
Organometallic Synthesis
As a Grignard reagent, 3-Methoxybenzylmagnesium chloride is a powerful nucleophile used to form new carbon-carbon bonds by reacting with electrophiles such as aldehydes, ketones, esters, and epoxides.
Pharmaceutical Intermediate Preparation
This compound serves as a key building block in the multi-step synthesis of complex pharmaceutical intermediates, facilitating the construction of novel molecular architectures.
Fine Chemical Synthesis
It is employed in the production of various fine chemicals where the 3-methoxybenzyl moiety is required, contributing to the development of specialized chemical products.
| Molecular weight | 180.91 |
|---|---|
| Linear formula | H3COC6H4CH2MgCl |
| Boiling point | 65 °C |
| Density | 0.904 g/mL at 25 °C |
| Concentration | 0.25 M in THF |
| Storage temperature | 2-8°C |
Hazard statements
- H225Highly flammable liquid and vapour
- H261In contact with water releases flammable gas
- H314Causes severe skin burns and eye damage
- H335May cause respiratory irritation
- H351Suspected of causing cancer
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P231Handle under inert gas
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P422
| Flash point | -17 °C / 1.4 °F |
|---|---|
| Transport (UN / ADR) | UN 2924 8(3) / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,Xn |
| Risk statements (R) | 11-19-36/37-40 |
| Safety statements (S) | 16-26-36/37 |
| Supplemental hazards | May form explosive peroxides. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-Methoxybenzylmagnesium chloride solution used for?
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3-Methoxybenzylmagnesium chloride solution is primarily used as a Grignard reagent in organic synthesis for introducing the 3-methoxybenzyl group into molecules, particularly in the preparation of pharmaceutical intermediates and fine chemicals.
What is the CAS number and formula for 3-Methoxybenzylmagnesium chloride solution?
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The CAS number is 26905-40-8 and the linear formula is H₃COC₆H₄CH₂MgCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 3-Methoxybenzylmagnesium chloride solution at a concentration of 0.25 M in THF. This product is intended for research and chemical synthesis purposes; TSS does not represent it as USP, BP, or EP grade.
How should 3-Methoxybenzylmagnesium chloride solution be handled?
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This is a highly flammable liquid and vapour (H225) and reacts violently with water (H261), causing severe skin burns and eye damage (H314). It may also cause respiratory irritation (H335) and is suspected of causing cancer (H351). Handle under an inert atmosphere, avoid contact with water, and use appropriate personal protective equipment. May form explosive peroxides.
How is 3-Methoxybenzylmagnesium chloride solution shipped and exported?
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3-Methoxybenzylmagnesium chloride solution is classified under UN 2924, Hazard Class 8 (Corrosive) with subsidiary hazard 3 (Flammable liquid), Packing Group II. TSS ensures compliant packaging and documentation for safe domestic and international export.
How can I request a sample or quote for 3-Methoxybenzylmagnesium chloride solution?
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To request a sample or a quote, please contact our sales department through the website or by phone, providing your specific requirements.
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