3-Methoxy-4-methylaniline
3-Methoxy-4-methylaniline (CAS: 16452-01-0) is an organic compound with the formula C8H11NO. This aromatic amine serves as a valuable building block in organic synthesis. Its structure, featuring methoxy and methyl substituents on an aniline core, allows for diverse chemical transformations. It is primarily utilised in the synthesis of more complex molecules within the pharmaceutical and chemical research sectors, contributing to the development of novel compounds.
- IUPAC
- 4-Methyl-m-anisidine,o-Cresidine

Organic Synthesis Intermediate
3-Methoxy-4-methylaniline is employed as a key intermediate in the multi-step synthesis of complex organic molecules. Its reactive amine group and substituted aromatic ring make it amenable to various coupling and functionalisation reactions.
Research and Development
This compound is utilised in academic and industrial research laboratories for the exploration of new chemical pathways and the creation of novel chemical entities. It serves as a versatile starting material for developing new pharmaceuticals and specialty chemicals.
Building Block for Heterocycles
The structure of 3-Methoxy-4-methylaniline makes it a suitable precursor for the synthesis of various nitrogen-containing heterocyclic compounds, which are prevalent in medicinal chemistry.
| Molecular weight | 137.18 |
|---|---|
| Empirical formula | C8H11NO |
| Assay | 98% |
| Melting point | 57-59 °C |

Hazard statements
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Flash point | >113 °C / >235.4 °F |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 20/21/22-36/37/38 |
| Safety statements (S) | 26-37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-Methoxy-4-methylaniline used for?
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3-Methoxy-4-methylaniline is used as a building block in organic synthesis and in research and development for creating new chemical entities, particularly in the pharmaceutical and specialty chemical industries.
What is the CAS number and formula for 3-Methoxy-4-methylaniline?
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The CAS number for 3-Methoxy-4-methylaniline is 16452-01-0, and its formula is C8H11NO.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 3-Methoxy-4-methylaniline with an assay of 98%. This product is supplied for research and laboratory use and is not represented as USP, BP, EP, or any other pharmacopoeia grade.
How should 3-Methoxy-4-methylaniline be handled?
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Handle 3-Methoxy-4-methylaniline with appropriate personal protective equipment. It is harmful if swallowed, in contact with skin, and if inhaled. It also causes skin irritation, serious eye irritation, and respiratory irritation. Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. In case of contact with eyes, rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. If eye irritation persists: Get medical advice/attention.
Is 3-Methoxy-4-methylaniline a controlled substance?
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Based on the provided data, there is no indication that 3-Methoxy-4-methylaniline is a controlled substance.
How is 3-Methoxy-4-methylaniline packed and exported?
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3-Methoxy-4-methylaniline is carefully packaged to maintain its integrity during transit. Tech Serve Solutions is experienced in exporting chemicals globally, adhering to international shipping regulations.
How can I request a quote or sample for 3-Methoxy-4-methylaniline?
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To request a quote or sample for 3-Methoxy-4-methylaniline, please contact our sales team through the website or by phone. Please specify the quantity required and your shipping details.
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