3-Maleimido-PROXYL
3-Maleimido-PROXYL (CAS: 5389-27-5), with the empirical formula C12H18N2O3 and a molecular weight of 238.28 g/mol, is a stable nitroxide radical. This compound serves as a valuable spin label for detailed investigations into local protein structures and the assessment of molecular alterations within erythrocyte membranes. Its paramagnetic nature allows for specific probing techniques in biochemical and biophysical research.
- IUPAC
- 3-Maleimido-2,2,5,5-tetramethyl-1-pyrrolidinyloxy, free radical

Biophysical Research
Utilised as a spin label to study local protein structures and dynamics. Its paramagnetic properties enable Electron Paramagnetic Resonance (EPR) spectroscopy for probing molecular environments.
Membrane Studies
Employed to determine molecular changes in erythrocyte membranes. It helps in understanding membrane fluidity, lipid interactions, and protein-lipid associations.
Chemical Synthesis
Acts as a synthetic reagent in radical chemistry. Its stable radical character can be incorporated into larger molecules or used in controlled radical reactions.
| Molecular weight | 238.28 |
|---|---|
| Empirical formula | C12H18N2O3 |
| Storage temperature | 2-8°C |
| Application | Spin label used for study of local protein structure and for determining molecular changes in erythrocyte membranes. |
| Melting point | 111-113 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-Maleimido-PROXYL primarily used for?
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3-Maleimido-PROXYL is primarily used as a spin label for studying local protein structures and for determining molecular changes in erythrocyte membranes.
What are the CAS number and formula for 3-Maleimido-PROXYL?
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The CAS number for 3-Maleimido-PROXYL is 5389-27-5, and its empirical formula is C12H18N2O3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 3-Maleimido-PROXYL as a technical or research grade material. We do not represent this product as USP, BP, or EP grade.
How should 3-Maleimido-PROXYL be handled safely?
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Handle 3-Maleimido-PROXYL with appropriate personal protective equipment, including a dust mask type N95 (US), eyeshields, and gloves. Ensure adequate ventilation as it may cause skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335).
How is 3-Maleimido-PROXYL packed and exported?
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3-Maleimido-PROXYL is packed according to industry best practices for chemical stability and safety during transport. Tech Serve Solutions is a global supplier and exporter, ensuring compliance with international shipping regulations.
How can I request a quote or sample?
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To request a quote or sample of 3-Maleimido-PROXYL, please contact our sales team through the website or by phone. Provide your specific requirements for prompt attention.
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