3-Hydroxybutyric acid
3-Hydroxybutyric acid (CAS: 300-85-6), with the linear formula CH <sub>3</sub>CH(OH)CH <sub>2</sub>COOH and a molecular weight of 104.10 g/mol, is a versatile organic building block. It is a carboxylic acid featuring a hydroxyl group, making it valuable in chemical synthesis. Available at 95% purity, this compound is employed in various research and development applications, particularly in organic synthesis pathways.
- IUPAC
- (±)-3-Hydroxybutanoic acid,DL-β-Hydroxybutyric acid
- Synonyms
- (±)-3-Hydroxybutanoic acidDL-β-Hydroxybutyric acid

Organic Synthesis Intermediate
3-Hydroxybutyric acid serves as a chiral building block in the enantioselective synthesis of complex organic molecules. Its bifunctional nature allows for diverse chemical transformations.
Biochemical Research
This compound is utilised in studies related to metabolic pathways and as a precursor in the production of biologically relevant molecules. Its use in the enantioselective synthesis of D-(-)-3-hydroxybutyric acid by Escherichia coli is documented.
Carbonyl and Carboxylic Acid Chemistry
As a member of the carbonyl and carboxylic acid families, it is a useful reagent for reactions involving these functional groups in academic and industrial research.
| Molecular weight | 104.10 |
|---|---|
| Linear formula | CH3CH(OH)CH2COOH |
| Assay | 95% |
| Boiling point | 118-120 °C/2 mmHg(lit.) |
| Density | 1.126 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.443(lit.) |
| Solubility | ethanol: soluble50 mg/mL, clear |
| Storage temperature | 2-8°C |
| Application | 3-Hydroxybutyric acid was used in enantioselective synthesis of D-(-)-3-hydroxybutyric acid by Escherichia coli1. |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 112 °C / 233.6 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-Hydroxybutyric acid used for?
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3-Hydroxybutyric acid is used as an organic building block and intermediate in chemical synthesis, particularly in enantioselective synthesis and biochemical research.
What is the CAS number and formula for 3-Hydroxybutyric acid?
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The CAS number is 300-85-6 and the linear formula is CH <sub>3</sub>CH(OH)CH <sub>2</sub>COOH.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 3-Hydroxybutyric acid with an assay of 95%. This product is intended for technical and research use; TSS does not represent it as USP, BP, EP, or pharmaceutical grade.
How should 3-Hydroxybutyric acid be handled safely?
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3-Hydroxybutyric acid is a Warning substance that causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Always use appropriate personal protective equipment, including eyeshields, gloves, and a suitable respirator. Ensure good ventilation.
How is 3-Hydroxybutyric acid shipped and exported by TSS?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 3-Hydroxybutyric acid. We handle all aspects of international shipping and export compliance.
How can I request a quote or sample for 3-Hydroxybutyric acid?
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To request a quote or a sample of 3-Hydroxybutyric acid, please contact our sales team through the website or by phone.
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