3-Fluoro-2-methylaniline
3-Fluoro-2-methylaniline (CAS 443-86-7) is a fluorinated aromatic amine with the molecular formula C7H8FN. This compound, with a molecular weight of 125.14 g/mol, serves as a valuable building block in organic synthesis. It is primarily utilised in research and development settings for the creation of novel chemical entities, particularly within the pharmaceutical and agrochemical industries, owing to the unique properties imparted by the fluorine atom.
- IUPAC
- 3-Fluoro-o-toluidine
Intermediate in Organic Synthesis
3-Fluoro-2-methylaniline is employed as a key intermediate in the synthesis of more complex organic molecules. Its amine and fluorine functionalities allow for diverse chemical transformations.
Pharmaceutical Research
This compound can be incorporated into the development of new pharmaceutical agents. The introduction of a fluorine atom can significantly influence a drug candidate's metabolic stability, lipophilicity, and binding affinity.
Agrochemical Development
As a building block, 3-Fluoro-2-methylaniline finds application in the research and synthesis of novel agrochemicals, potentially leading to new pesticides or herbicides with improved efficacy.
Material Science
Fluorinated organic compounds are of interest in material science for their unique electronic and physical properties. This aniline derivative may be explored for applications in specialised polymers or electronic materials.
| Molecular weight | 125.14 |
|---|---|
| Linear formula | FC6H3(CH3)NH2 |
| Assay | 99% |
| Boiling point | 89-91 °C/15 mmHg(lit.) |
| Density | 1.099 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.542(lit.) |
| Application | 3-Fluoro-2-methylaniline was used in the synthesis of 2-amino-1,7,9-trimethylimidazo[4,5-g]quinoxaline1. |
| Melting point | 7 °C(lit.) |
Hazard statements
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H315Causes skin irritation
- H319Causes serious eye irritation
- H332Harmful if inhaled
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 86 °C / 186.8 °F |
| Transport (UN / ADR) | NA 1993 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 20/21/22-36/37/38 |
| Safety statements (S) | 26-36/37 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-Fluoro-2-methylaniline used for?
+
3-Fluoro-2-methylaniline is used as an intermediate in organic synthesis, particularly in pharmaceutical and agrochemical research and development, and potentially in material science.
What are the CAS number and molecular formula for 3-Fluoro-2-methylaniline?
+
The CAS number is 443-86-7 and the molecular formula is C7H8FN.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies 3-Fluoro-2-methylaniline with an assay of 99%. It is not represented as USP, BP, or EP grade.
How should 3-Fluoro-2-methylaniline be handled safely?
+
Handle 3-Fluoro-2-methylaniline with appropriate personal protective equipment, including eyeshields, faceshields, gloves, and a suitable respirator. It is classified as harmful if swallowed, in contact with skin, or if inhaled, and causes skin and eye irritation, and may cause respiratory irritation (H302, H312, H315, H319, H332, H335).
Is 3-Fluoro-2-methylaniline a controlled substance?
+
The provided data does not indicate that 3-Fluoro-2-methylaniline is a controlled substance.
How is 3-Fluoro-2-methylaniline shipped and exported?
+
3-Fluoro-2-methylaniline is shipped as per its classification, including NA 1993 requirements. Tech Serve Solutions is experienced in global export.
How can I request a sample or quote for 3-Fluoro-2-methylaniline?
+
Please contact our sales team through the website or by phone to request a sample or a quotation for 3-Fluoro-2-methylaniline.
▶ Related products
1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis
1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis