3-[(E)-[[(1R,2R)-2-[[(1S)-1-[(Dimethylamino)carbonyl]-2,2-dimethylpropyl]thioureido]cyclohexyl]imino]methyl]-5-(tert-butyl)-4-hydroxyphenyl pivalate
3-[(E)-[[(1R,2R)-2-[[(1S)-1-[(Dimethylamino)carbonyl]-2,2-dimethylpropyl]thioureido]cyclohexyl]imino]methyl]-5-(tert-butyl)-4-hydroxyphenyl pivalate (CAS 462632-54-8) is a chiral thiourea derivative with a molecular weight of 574.82 g/mol. It is primarily utilised as a catalyst in asymmetric synthesis, specifically for facilitating the Strecker reaction with high enantioselectivity. This compound is supplied by Tech Serve Solutions for research and development purposes, offering a high assay of 95%.
- IUPAC
- 3-[[[(1R,2R)-2-[[[[(1S)-1-[(Dimethylamino)carbonyl]-2,2-dimethylpropyl]amino]thioxomethyl]amino]cyclohexyl]imino]methyl]-5-(1,1-dimethylethyl)-4-hydroxyphenyl 2,2-dimethylpropanoate
- Synonyms
- 462632-54-8C31H50N4O4S
![3-[(E)-[[(1R,2R)-2-[[(1S)-1-[(Dimethylamino)carbonyl]-2,2-dimethylpropyl]thioureido]cyclohexyl]imino]methyl]-5-(tert-butyl)-4-hydroxyphenyl pivalate (C31H50N4O4S) — chemical structure, CAS 462632-54-8; Chemistry, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F462632-54-8.png&w=3840&q=75)
Catalyst for Asymmetric Synthesis
This compound serves as an effective chiral catalyst in asymmetric synthesis. Its specific application includes promoting the enantioselective Strecker reaction, a crucial transformation for generating chiral alpha-amino acids.
Jacobsen Thiourea Ligand
As a member of the Jacobsen thiourea class, this molecule functions as a chiral ligand. Such ligands are instrumental in developing novel catalytic systems for stereoselective chemical transformations in organic synthesis.
Chemical Synthesis Reagent
Beyond its catalytic role, this compound can be employed as a reagent in complex chemical syntheses. Its stereochemical features make it valuable for introducing chirality in target molecules.
| Molecular weight | 574.82 |
|---|---|
| Empirical formula | C31H50N4O4S |
| Assay | 95% |
| Optical activity | [α]20/D -88°, c = 1 in chloroform |
| Application | Catalyst for the Strecker reaction1 |
| Melting point | 135-138 °C (D) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36/37 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Mw Mn | <1.2 |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-[(E)-[[(1R,2R)-2-[[(1S)-1-[(Dimethylamino)carbonyl]-2,2-dimethylpropyl]thioureido]cyclohexyl]imino]methyl]-5-(tert-butyl)-4-hydroxyphenyl pivalate used for?
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This compound is primarily used as a chiral catalyst for the asymmetric Strecker reaction and as a ligand in asymmetric synthesis.
What is the CAS number and molecular formula for this product?
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The CAS number is 462632-54-8 and the empirical formula (Hill notation) is C31H50N4O4S.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product with an assay of 95%. It is supplied for research and development; TSS does not represent it as USP, BP, EP, or other pharmacopoeia grades.
How should this chemical be handled safely?
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This compound is classified as a Warning. It may cause skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). Use a dust mask type N95 (US), eyeshields, and gloves when handling. Ensure adequate ventilation.
Is this chemical supplied internationally?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals.
How can I request a sample or quote?
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To request a sample or a quotation, please contact our sales department through the website or by phone, providing the product name and CAS number.
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