3-(Dimethylamino)-1,2-propanediol

CAS 623-57-4(CH3)2NCH2CH(OH)CH2OHChemical Synthesis

3-(Dimethylamino)-1,2-propanediol (CAS 623-57-4) is an organic compound with the linear formula (CH3)2NCH2CH(OH)CH2OH and a molecular weight of 119.16 g/mol. This amino alcohol serves as a valuable building block in organic synthesis. Its applications include the preparation of specialised molecules for research, such as synthetic cationic lipids for transfection protocols and indane-derived bis(oxazolines). Tech Serve Solutions offers this chemical with a typical assay of 98%.

Synonyms: (CH3)2NCH2CH(OH)CH2OH

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3-(Dimethylamino)-1,2-propanediol ((CH3)2NCH2CH(OH)CH2OH) — chemical structure, CAS 623-57-4; Chemistry, fine chemical supplied by Tech Serve Solutions

Amino AlcoholsBuilding BlocksChemical SynthesisOrganic Building BlocksOxygen Compounds

01 /Applications

Synthetic Cationic Lipid Preparation

Used in the preparation of synthetic cationic lipids like DOTMA, which is employed in DNA-transfection protocols. This application highlights its utility in biochemical and molecular biology research.

Organic Synthesis Building Block

Serves as a versatile building block for the synthesis of complex organic molecules. Its structure, featuring both amino and diol functionalities, allows for diverse chemical transformations.

Preparation of Bis(oxazolines)

3-(Dimethylamino)-1,2-propanediol has been utilised in the synthesis of indane-derived bis(oxazolines), indicating its role in the development of novel ligands or chiral auxiliaries.

02 /Properties

Molecular weight	119.16
Linear formula	(CH3)2NCH2CH(OH)CH2OH
Assay	98%
Boiling point	216-217 °C(lit.)
Density	1.004 g/mL at 25 °C(lit.)
Refractive index	n20/D 1.4609(lit.)
Application	3-(Dimethylamino)-1,2-propanediol was used in the preparation of:• synthetic cationic lipid, N-[1-(2,3-dioleyloxy)propyl-N,N,N-trimethylammonium chloride (DOTMA), used in DNA-transfection protocol1• indane-derived bis(oxazolines)2

03 /Safety & handling

GHS hazard pictogram: Corrosive (GHS05) — Corrosive

Danger

Hazard statements

H314Causes severe skin burns and eye damage

Precautionary statements

P280Wear protective gloves, clothing and eye/face protection
P305IF IN EYES
P310Immediately call a POISON CENTER or doctor

Protective equipment	Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
Flash point	105 °C / 221 °F
Transport (UN / ADR)	UN 3267 8 / PGII
Water hazard class (WGK, DE)	3
Hazard codes (EU)	C
Risk statements (R)	34
Safety statements (S)	23-26-27-36/37/39-45

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

623-57-4

MDL number

MFCD00004714

PubChem substance

24852622

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is 3-(Dimethylamino)-1,2-propanediol used for?

3-(Dimethylamino)-1,2-propanediol is primarily used as a building block in organic synthesis, including the preparation of synthetic cationic lipids for DNA transfection and indane-derived bis(oxazolines).

What is the CAS number and formula for 3-(Dimethylamino)-1,2-propanediol?

The CAS number is 623-57-4, and its linear formula is (CH3)2NCH2CH(OH)CH2OH.

What grade and purity does Tech Serve Solutions supply for 3-(Dimethylamino)-1,2-propanediol?

Tech Serve Solutions supplies 3-(Dimethylamino)-1,2-propanediol with an assay of 98%. This product is intended for research and chemical synthesis purposes and is not represented as USP, BP, or EP grade.

What are the primary safety hazards associated with 3-(Dimethylamino)-1,2-propanediol?

This compound is classified as corrosive, indicated by GHS05 symbol and hazard statement H314, meaning it causes severe skin burns and eye damage. Appropriate personal protective equipment, including face shields, gloves, and respiratory protection, is essential during handling.

How is 3-(Dimethylamino)-1,2-propanediol packed and shipped?

3-(Dimethylamino)-1,2-propanediol is shipped as UN 3267, Class 8, Packing Group II, indicating it is a corrosive liquid, basic, organic, n.o.s. Specific packaging suitable for hazardous materials is used to ensure safe transport and export.

How can I request a sample or quote for 3-(Dimethylamino)-1,2-propanediol?

To request a sample or a quotation, please contact our sales team through the website or by phone, providing the product name and CAS number (623-57-4).