3-Chloro-N,N-bis(trimethylsilyl)aniline
3-Chloro-N,N-bis(trimethylsilyl)aniline (CAS: 7522-27-2) is a versatile organic compound with the molecular formula C12H22ClNSi2 and a molecular weight of 271.93 g/mol. This protected aniline derivative serves as a key building block in organic synthesis. Its primary application involves its use in the preparation of the corresponding Grignard reagent, facilitating further chemical transformations. Available from Tech Serve Solutions, it is supplied at a purity of 98%.
- Synonyms
- N-(3-chlorophenyl)-1,1,1-tris(trimethylsiloxy)silanamine3-Chloro-N,N-bis(trimethylsilyl)anilineClC6H4N[Si(CH3)3]2
![3-Chloro-N,N-bis(trimethylsilyl)aniline (ClC6H4N[Si(CH3)3]2) — chemical structure, CAS 7522-27-2; Chemistry, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F7522-27-2.png&w=3840&q=75)
Grignard Reagent Preparation
This compound is specifically suited for the preparation of its corresponding Grignard reagent. This transformation is a fundamental step in many organometallic syntheses, enabling carbon-carbon bond formation.
Organic Synthesis Intermediate
As a functionalised aniline derivative, it acts as a valuable intermediate in complex organic synthesis pathways. The presence of the chlorine atom and the protected amine group allows for selective functionalization and elaboration.
Building Block for Nitrogen Compounds
Its structure makes it a useful building block for constructing more complex nitrogen-containing molecules. It is particularly relevant in research and development settings for creating novel chemical entities.
| Molecular weight | 271.93 |
|---|---|
| Linear formula | ClC6H4N[Si(CH3)3]2 |
| Assay | 98% |
| Boiling point | 85 °C/0.4 mmHg(lit.) |
| Density | 0.981 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.5(lit.) |
| Application | Suitable for preparation of the corresponding Grignard reagent. |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 104 °C / 219.2 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-Chloro-N,N-bis(trimethylsilyl)aniline used for?
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3-Chloro-N,N-bis(trimethylsilyl)aniline is primarily used as a building block in organic synthesis, particularly for the preparation of the corresponding Grignard reagent and for creating more complex nitrogen-containing compounds.
What is the CAS number and chemical formula for this compound?
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The CAS number is 7522-27-2, and its linear formula is ClC6H4N[Si(CH3)3]2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 3-Chloro-N,N-bis(trimethylsilyl)aniline with an assay of 98%. We do not represent this product as USP, BP, or EP grade.
How should 3-Chloro-N,N-bis(trimethylsilyl)aniline be handled safely?
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This compound is classified with hazard statements H315 (Causes skin irritation), H319 (Causes serious eye irritation), and H335 (May cause respiratory irritation). It is advised to wear appropriate personal protective equipment, including eyeshields and gloves, and to handle it in a well-ventilated area or with respiratory protection.
Is this chemical exported by Tech Serve Solutions?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 3-Chloro-N,N-bis(trimethylsilyl)aniline.
How can I request a sample or quote for 3-Chloro-N,N-bis(trimethylsilyl)aniline?
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To request a sample or a quotation, please contact our sales department via the website or by calling our customer service line.
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