3-Chloro-D-alanine methyl ester hydrochloride
3-Chloro-D-alanine methyl ester hydrochloride (CAS: 112346-82-4) is a halogenated, unnatural amino acid derivative with the molecular formula C4H8ClNO2·HCl and a molecular weight of 174.03 g/mol. This compound serves as a valuable chiral building block in organic synthesis, particularly in the fields of peptide chemistry and chemical biology. Its structure allows for incorporation into peptides to modify their properties or explore novel biological activities.
- IUPAC
- 3-Chloro-D-Ala-OMe hydrochloride,β-Chloro-D-alanine methyl ester hydrochloride,(S)-Methyl 2-amino-3-chloropropanoate hydrochloride,(S)-Methyl 2-amino-3-chloropropionate hydrochloride
- Synonyms
- (S)-Methyl 2-amino-3-chloropropanoate hydrochloride(S)-Methyl 2-amino-3-chloropropionate hydrochloride3-Chloro-D-Ala-OMe hydrochlorideβ-Chloro-D-alanine methyl ester hydrochloride
Chiral Building Block in Organic Synthesis
Utilised as a precursor for the synthesis of complex organic molecules, leveraging its specific stereochemistry and functional groups. It is particularly useful for introducing modified alanine residues into peptide chains.
Peptide Chemistry
Incorporated into synthetic peptides to create peptidomimetics or peptides with enhanced stability, altered biological activity, or novel structural features.
Chemical Biology Research
Employed in studies investigating protein function, enzyme mechanisms, or developing new biochemical probes due to its unnatural amino acid nature.
Drug Discovery Intermediate
Serves as an intermediate in the synthesis of potential pharmaceutical agents, where the chlorinated alanine motif can confer specific pharmacological properties.
| Molecular weight | 174.03 |
|---|---|
| Empirical formula | C4H8ClNO2·HCl |
| Assay | 97% |
| Optical activity | [α]22/D +4.5°, c = 0.5% in DMSO |
| Storage temperature | 2-8°C |
| Melting point | 143-148 °C |
Hazard statements
- H302Harmful if swallowed
- H317May cause an allergic skin reaction
- H319Causes serious eye irritation
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Water hazard class (WGK, DE) | 3 |
|---|---|
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-36-43 |
| Safety statements (S) | 26-36/37 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-Chloro-D-alanine methyl ester hydrochloride used for?
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3-Chloro-D-alanine methyl ester hydrochloride is primarily used as a chiral building block in organic synthesis, for peptide chemistry research, and in chemical biology studies. It serves as an intermediate in the synthesis of modified peptides and potential pharmaceutical compounds.
What are the CAS number and molecular formula for this compound?
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The CAS number for 3-Chloro-D-alanine methyl ester hydrochloride is 112346-82-4. Its empirical formula is C4H8ClNO2·HCl, and its molecular weight is 174.03 g/mol.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 3-Chloro-D-alanine methyl ester hydrochloride with an assay of 97%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
What are the safety considerations when handling this chemical?
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This compound is classified with a Warning signal word. It is harmful if swallowed (H302), may cause an allergic skin reaction (H317), and causes serious eye irritation (H319). Appropriate personal protective equipment, including gloves and eye protection, should be worn. Ensure adequate ventilation.
How is 3-Chloro-D-alanine methyl ester hydrochloride shipped or exported?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals. We handle all shipping and export logistics in compliance with international regulations.
How can I request a sample or a quote for this product?
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Please use the 'Request a Quote' or 'Request a Sample' form on our website, or contact our sales team directly with your specific requirements.
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