3-Bromopropionyl chloride
3-Bromopropionyl chloride (CAS: 15486-96-1), with the molecular formula BrCH₂CH₂COCl and a molar mass of 171.42 g/mol, is a reactive acyl halide. It serves as a versatile building block in organic synthesis, primarily utilised in the preparation of various chemical intermediates. Its applications span chemical synthesis, making it a valuable reagent for researchers and industrial chemists. TSS provides this compound for laboratory and industrial applications.
Synthesis of Heterocyclic Compounds
3-Bromopropionyl chloride can be employed in cyclisation reactions to form various heterocyclic structures, which are important motifs in pharmaceuticals and agrochemicals.
Preparation of Functionalised Ketones
As demonstrated in literature, it has been used in the preparation of functionalised ketones, such as 1-chloro-4-bromo-2-butanone, serving as a key intermediate in multi-step synthetic pathways.
Organic Building Block
Its bifunctional nature, featuring a reactive acid chloride and an alkyl bromide, makes it a useful organic building block for introducing specific functional groups into target molecules.
| Molecular weight | 171.42 |
|---|---|
| Linear formula | BrCH2CH2COCl |
| Boiling point | 55-57 °C/17 mmHg(lit.) |
| Density | 1.701 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.49(lit.) |
| Storage temperature | 2-8°C |
| Application | 3-Bromopropionyl chloride was used in the preparation of 1-chloro-4-bromo-2-butanone1. |
Hazard statements
- H314Causes severe skin burns and eye damage
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 79 °C / 174.2 °F |
| Transport (UN / ADR) | UN 3265 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34-36/37 |
| Safety statements (S) | 23-26-27-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-Bromopropionyl chloride primarily used for?
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3-Bromopropionyl chloride is primarily used as a building block in organic synthesis, including the preparation of functionalised ketones and heterocyclic compounds.
What is the CAS number and chemical formula for 3-Bromopropionyl chloride?
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The CAS number is 15486-96-1 and the linear formula is BrCH₂CH₂COCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 3-Bromopropionyl chloride typically as a technical or research grade. We do not represent it as USP, BP, or EP grade unless explicitly stated on the product documentation.
How should 3-Bromopropionyl chloride be handled safely?
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3-Bromopropionyl chloride is corrosive and may cause severe burns and eye damage. It is also irritating to the respiratory tract. Handle with appropriate personal protective equipment, including gloves, eye protection (face shield/goggles), and respiratory protection in a well-ventilated area or fume hood. Refer to the Safety Data Sheet (SDS) for full details.
How is 3-Bromopropionyl chloride packed and exported?
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3-Bromopropionyl chloride is packaged according to international shipping regulations for hazardous materials and exported globally by TSS.
How can I request a quote or sample of 3-Bromopropionyl chloride?
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To request a quote or sample, please contact the Tech Serve Solutions sales team via our website or direct contact details, specifying the product and quantity required.
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