3-Bromophenylzinc iodide solution
3-Bromophenylzinc iodide (CAS: 186000-44-2, Formula: BrC6H4Znl, MW: 348.29) is an organometallic reagent supplied as a 0.5 M solution in THF. It is a valuable tool in organic synthesis, particularly for forming new carbon-carbon bonds through cross-coupling reactions. Its utility extends to various chemical synthesis applications, making it a key intermediate for complex molecule construction in research and development.
Organozinc Halide Reagent
3-Bromophenylzinc iodide serves as an organozinc halide reagent, enabling the introduction of the 3-bromophenyl group into organic molecules. This is commonly achieved through palladium-catalyzed cross-coupling reactions, such as Negishi coupling.
Carbon-Carbon Bond Formation
This reagent is instrumental in the formation of carbon-carbon bonds, a fundamental transformation in organic chemistry. Its reactivity profile allows for controlled coupling with various organic electrophiles, facilitating the synthesis of complex molecular architectures.
Pharmaceutical Intermediate Synthesis
The ability to precisely functionalize aromatic rings makes 3-bromophenylzinc iodide a useful intermediate in the synthesis of pharmaceutical compounds. It allows for the modular construction of drug candidates and their analogues.
Material Science Research
Organozinc reagents are employed in the development of novel materials. 3-Bromophenylzinc iodide can be used in the synthesis of monomers or building blocks for polymers and other advanced materials with tailored electronic or optical properties.
| Molecular weight | 348.29 |
|---|---|
| Linear formula | BrC6H4Znl |
| Boiling point | 65 °C |
| Density | 1.023 g/mL at 25 °C |
| Concentration | 0.5 M in THF |
| Storage temperature | 2-8°C |
Hazard statements
- H225Highly flammable liquid and vapour
- H319Causes serious eye irritation
- H335May cause respiratory irritation
- H351Suspected of causing cancer
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P261Avoid breathing dust, fume, gas or vapours
- P281Use personal protective equipment as required
- P305IF IN EYES
| Flash point | -17 °C / 1.4 °F |
|---|---|
| Transport (UN / ADR) | UN 2056 3 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,Xn |
| Risk statements (R) | 11-19-36/37-40 |
| Safety statements (S) | 16-26-36/37 |
| Supplemental hazards | May form explosive peroxides. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-Bromophenylzinc iodide solution used for?
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3-Bromophenylzinc iodide solution (CAS: 186000-44-2) is primarily used as an organometallic reagent in organic synthesis, particularly for carbon-carbon bond formation via cross-coupling reactions and as an intermediate in the synthesis of pharmaceuticals and materials.
What are the CAS number and formula for 3-Bromophenylzinc iodide?
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The CAS number for 3-Bromophenylzinc iodide is 186000-44-2, and its linear formula is BrC6H4Znl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 3-Bromophenylzinc iodide as a 0.5 M solution in THF. TSS does not represent this product as USP, BP, or EP grade; it is suitable for research and chemical synthesis purposes.
What are the main safety hazards associated with this product?
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This product is highly flammable (H225) with a low flash point (-17 °C). It can cause serious eye irritation (H319) and may cause respiratory irritation (H335). There is also a suspicion of causing cancer (H351). It may form explosive peroxides, and containers should be stored under inert gas.
How is 3-Bromophenylzinc iodide solution shipped and exported?
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3-Bromophenylzinc iodide solution is classified under UN 2056, Hazard Class 3, Packing Group II. It is shipped and exported according to stringent international regulations for hazardous and flammable materials, typically under an inert atmosphere.
How can I request a sample or a quote for 3-Bromophenylzinc iodide solution?
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To request a sample or obtain a quote for 3-Bromophenylzinc iodide solution, please contact our sales department via the website or email, specifying the quantity and delivery location.
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