3-Bromobenzyl bromide
3-Bromobenzyl bromide (CAS: 823-78-9), with the molecular formula BrC6H4CH2Br and a molecular weight of 249.93 g/mol, is a halogenated hydrocarbon. This organic compound serves as a valuable building block in chemical synthesis. It is employed in the preparation of complex molecules, including substituted quinolines with potential pharmaceutical applications and macrocyclic compounds. Available from Tech Serve Solutions, it meets a high purity standard for research and development purposes.
- IUPAC
- α,3-Dibromotoluene
- Synonyms
- α,3-Dibromotoluene
Synthesis of Macrocyclic Compounds
3-Bromobenzyl bromide has been utilised in the synthesis of macrocyclic compounds such as 1,7-di(3-bromobenzyl)cyclen. This application highlights its utility in constructing complex ring systems for further chemical exploration.
Preparation of Pharmaceutical Intermediates
The compound is a key intermediate in the synthesis of substituted 8-arylquinolines. These structures have been investigated for their potential as phosphodiesterase 4 (PDE4) inhibitors, indicating its role in medicinal chemistry research.
Organic Building Block in Synthesis
As a versatile aryl halide, 3-Bromobenzyl bromide is a fundamental building block for introducing bromobenzyl moieties into organic molecules. Its reactivity makes it suitable for various coupling and substitution reactions in multi-step syntheses.
| Molecular weight | 249.93 |
|---|---|
| Linear formula | BrC6H4CH2Br |
| Assay | 99% |
| Application | 3-Bromobenzyl bromide was used in the synthesis of:• 1,7-di(3-bromobenzyl)cyclen1• substituted 8-arylquinoline, phosphodiesterase 4 (PDE4) inhibitors2 |
| Melting point | 39-41 °C(lit.) |
Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Flash point | 113 °C / 235.4 °F |
| Transport (UN / ADR) | UN 3261 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34-37 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-Bromobenzyl bromide used for?
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3-Bromobenzyl bromide is used as a building block in organic synthesis, notably in the preparation of macrocyclic compounds and substituted 8-arylquinolines, which have been explored for their potential as phosphodiesterase 4 (PDE4) inhibitors.
What are the CAS number and formula for 3-Bromobenzyl bromide?
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The CAS number for 3-Bromobenzyl bromide is 823-78-9, and its molecular formula is BrC6H4CH2Br.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 3-Bromobenzyl bromide with an assay of 99%. This product is intended for research and laboratory use; TSS does not represent it as USP, BP, or EP grade.
How should 3-Bromobenzyl bromide be handled safely?
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3-Bromobenzyl bromide is classified as Danger (GHS05) and causes severe skin burns and eye damage (H314). Safe handling requires stringent personal protective equipment, including eyeshields, face shields, suitable gloves, and respiratory protection (e.g., N100 respirator). Always refer to the Safety Data Sheet before use.
Is 3-Bromobenzyl bromide exported by TSS?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 3-Bromobenzyl bromide.
How can I request a quote or sample for 3-Bromobenzyl bromide?
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To request a quote or a sample of 3-Bromobenzyl bromide, please contact our sales department through the website or by telephone. Our team will be happy to assist you with your chemical requirements.
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