3-Bromobenzoyl chloride
3-Bromobenzoyl chloride (CAS: 1711-09-7), with the molecular formula BrC₆H₄COCl and a molecular weight of 219.46 g/mol, is a valuable organic building block. This acid halide is characterised by its reactive acyl chloride group, making it a key intermediate in organic synthesis. It is primarily utilised in the development of complex molecules and pharmaceutical intermediates, enabling the introduction of the 3-bromobenzoyl moiety into target structures.
Synthesis of Oxadiazole Derivatives
3-Bromobenzoyl chloride serves as a crucial reactant in the synthesis of heterocyclic compounds. It has been employed in the preparation of 2-(3-bromophenyl)-5-phenyl-1,3,4-oxadiazole, a process that highlights its utility in constructing complex organic frameworks.
Preparation of Diazepane Compounds
This chemical intermediate is instrumental in the synthesis of various organic structures, including those with diazepane rings. Notably, it has been utilised in the preparation of (4-benzhydryl-1,4-diazepan-1-yl)(3-bromophenyl)methanone, demonstrating its application in medicinal chemistry research.
Organic Synthesis Intermediate
As a versatile building block, 3-Bromobenzoyl chloride is widely used in general organic synthesis. Its reactivity allows for facile derivatisation, making it an essential reagent for introducing the 3-bromobenzoyl group into a range of organic molecules.
| Molecular weight | 219.46 |
|---|---|
| Linear formula | BrC6H4COCl |
| Assay | ≥98.0% (HPLC/T) |
| Boiling point | 74-75 °C/0.5 mmHg(lit.) |
| Density | 1.662 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.595(lit.) |
| Application | 3-Bromobenzoyl chloride was used in the synthesis of 2-(3-bromophenyl)-5-phenyl-1,3,4-oxadiazole1 and (4-benzhydryl-1,4-diazepan-1-yl)(3-bromophenyl)methanone2. |
Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 107 °C / 224.6 °F |
| Transport (UN / ADR) | UN 3265 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34-37 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-Bromobenzoyl chloride used for?
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3-Bromobenzoyl chloride is primarily used as an intermediate in organic synthesis, particularly for the preparation of heterocyclic compounds like oxadiazoles and complex molecules containing the 3-bromobenzoyl moiety. It is also employed in the synthesis of diazepane derivatives.
What are the CAS number and formula for 3-Bromobenzoyl chloride?
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The CAS number for 3-Bromobenzoyl chloride is 1711-09-7, and its linear formula is BrC₆H₄COCl.
What grade and purity does Tech Serve Solutions supply for 3-Bromobenzoyl chloride?
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Tech Serve Solutions supplies 3-Bromobenzoyl chloride with a purity of ≥98.0% (HPLC/T). We do not represent this product as USP, BP, or EP grade.
How should 3-Bromobenzoyl chloride be handled safely?
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3-Bromobenzoyl chloride is a corrosive substance that causes severe skin burns and eye damage (H314). Handling requires stringent safety measures, including the use of full-face respirators, chemical-resistant gloves, goggles, and face shields. It is essential to avoid contact with skin, eyes, and clothing, and to work in a well-ventilated area.
Is 3-Bromobenzoyl chloride a controlled substance?
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The provided data does not indicate that 3-Bromobenzoyl chloride is a controlled substance.
How is 3-Bromobenzoyl chloride packed, shipped, and exported?
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3-Bromobenzoyl chloride is classified under UN 3265, Packing Group II, for transport. Tech Serve Solutions adheres to all international shipping regulations for hazardous materials, ensuring safe and compliant packaging, shipping, and export.
How can I request a sample or quote for 3-Bromobenzoyl chloride?
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To request a sample or a quote for 3-Bromobenzoyl chloride, please contact our sales team through the website or by phone, providing your specific requirements and shipping details.
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