3-Bromo-5-(trifluoromethyl)pyridine
3-Bromo-5-(trifluoromethyl)pyridine (CAS 436799-33-6) is a halogenated heterocyclic compound with the formula C6H3BrF3N and a molecular weight of 225.99 g/mol. This pyridine derivative serves as a valuable building block in organic synthesis, particularly in the preparation of more complex molecules. Its structure, featuring both a bromine atom and a trifluoromethyl group on the pyridine ring, offers unique reactivity for various chemical transformations.
Organic Synthesis Intermediate
Utilised as a key intermediate in the synthesis of novel organic compounds. The bromine atom allows for cross-coupling reactions, while the trifluoromethyl group can influence electronic properties and lipophilicity of target molecules.
Pharmaceutical Building Block
Serves as a structural motif in the development of new pharmaceutical agents. Its incorporation into drug candidates can modulate pharmacokinetic and pharmacodynamic profiles.
Agrochemical Research
Employable in the design and synthesis of new agrochemicals, leveraging its heterocyclic and fluorinated nature to potentially enhance efficacy and stability.
| Molecular weight | 225.99 |
|---|---|
| Empirical formula | C6H3BrF3N |
| Assay | 97% |
| Application | Prepared from iodobromopyridine by iodide displacement with in situ generated (trifluoromethyl)copper.1 |
| Melting point | 44-46 °C |
Hazard statements
- H300Fatal if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P264Wash thoroughly after handling
- P301IF SWALLOWED
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges |
|---|---|
| Flash point | 85 °C / 185 °F |
| Transport (UN / ADR) | UN 2811 6.1 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 25-36/37/38 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-Bromo-5-(trifluoromethyl)pyridine used for?
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3-Bromo-5-(trifluoromethyl)pyridine is primarily used as a building block and intermediate in organic synthesis, particularly for pharmaceuticals and agrochemicals.
What is the CAS number and molecular formula for 3-Bromo-5-(trifluoromethyl)pyridine?
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The CAS number is 436799-33-6 and the molecular formula is C6H3BrF3N.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 3-Bromo-5-(trifluoromethyl)pyridine with an assay of 97%. This product is not classified as USP, BP, or EP grade.
How should 3-Bromo-5-(trifluoromethyl)pyridine be handled?
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Handling requires caution due to its hazards. It is toxic if swallowed, causes skin irritation, and can cause serious eye irritation and respiratory irritation. Recommended personal protective equipment includes eyeshields, faceshields, gloves, and a P2 respirator. Ensure good ventilation.
Is 3-Bromo-5-(trifluoromethyl)pyridine a controlled substance?
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The provided data does not indicate that 3-Bromo-5-(trifluoromethyl)pyridine is a controlled substance.
How is 3-Bromo-5-(trifluoromethyl)pyridine shipped?
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Based on its UN classification (UN 2811, 6.1, PGIII), it is shipped as a toxic substance, requiring specific packaging and labelling protocols.
How can I request a sample or quote for 3-Bromo-5-(trifluoromethyl)pyridine?
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Please contact the Tech Serve Solutions sales team directly to request a sample or a formal quotation for 3-Bromo-5-(trifluoromethyl)pyridine.
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