3-Bromo-5-(trifluoromethyl)benzenesulfonyl chloride
3-Bromo-5-(trifluoromethyl)benzenesulfonyl chloride (CAS: 351003-46-8), with the molecular formula CF3C6H3(Br)SO2Cl and a molecular weight of 323.51 g/mol, is a key organic building block. This trifluoromethylated and brominated benzenesulfonyl chloride derivative is primarily utilised in organic synthesis, serving as a versatile intermediate for creating more complex molecules in research and development settings. Its reactive sulfonyl chloride group allows for diverse chemical transformations.
Organic Synthesis Intermediate
Serves as a crucial building block in the synthesis of complex organic molecules. Its structure, featuring both bromine and a trifluoromethyl group on a benzenesulfonyl chloride core, offers unique reactivity for derivatisation.
Pharmaceutical Research
Employed in the development of novel pharmaceutical agents. The trifluoromethyl group can enhance metabolic stability and lipophilicity, making it a valuable moiety in drug discovery.
Agrochemical Development
Used in the creation of new agrochemical compounds. The specific substitution pattern may contribute to the biological activity of pesticides or herbicides.
Material Science
Potentially used in the synthesis of functional materials where its specific electronic or structural properties can be leveraged.
| Molecular weight | 323.51 |
|---|---|
| Linear formula | CF3C6H3(Br)SO2Cl |
| Assay | 97% |
| Boiling point | 217-218 °C(lit.) |
| Density | 1.835 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.5240(lit.) |
Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 65 °C / 149 °F |
| Transport (UN / ADR) | UN 3265 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 14-34 |
| Safety statements (S) | 22-26-36/37/39-45 |
| Supplemental hazards | Reacts violently with water. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-Bromo-5-(trifluoromethyl)benzenesulfonyl chloride used for?
+
This compound is primarily used as a versatile building block and intermediate in organic synthesis, particularly in the research and development of pharmaceuticals and agrochemicals.
What are the CAS number and formula for this chemical?
+
The CAS number is 351003-46-8 and the molecular formula is CF3C6H3(Br)SO2Cl.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies this chemical with an assay of 97%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should 3-Bromo-5-(trifluoromethyl)benzenesulfonyl chloride be handled safely?
+
This compound is classified as Danger (GHS05) and causes severe skin burns and eye damage (H314). It reacts violently with water. Always use appropriate personal protective equipment, including faceshields, gloves, goggles, and a suitable respirator, and handle in a well-ventilated area, strictly avoiding contact with water.
How is this chemical shipped and exported?
+
3-Bromo-5-(trifluoromethyl)benzenesulfonyl chloride is shipped under UN 3265, Class 8, Packing Group II (Corrosive liquid, acidic, organic, n.o.s.). TSS is experienced in global export procedures for hazardous materials.
How can I request a sample or quote?
+
Please contact Tech Serve Solutions directly via our website or sales team to request a sample or a quotation for 3-Bromo-5-(trifluoromethyl)benzenesulfonyl chloride.
▶ Related products
1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis
1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis