3-Biphenylmagnesium bromide
3-Biphenylmagnesium bromide (CAS: 103068-18-4) is an organometallic compound with a molecular weight of 257.41 g/mol. Supplied as a solution in Tetrahydrofuran (THF), this Grignard reagent is a valuable tool in organic synthesis. It serves as a versatile source of the biphenyl anion for carbon-carbon bond formation, enabling the construction of complex organic molecules in research and development settings.
Grignard Reagent in Organic Synthesis
As a Grignard reagent, 3-Biphenylmagnesium bromide readily reacts with electrophiles such as aldehydes, ketones, esters, and epoxides. This reactivity allows for the efficient introduction of the biphenyl moiety into organic structures, facilitating the synthesis of pharmaceuticals and advanced materials.
Synthesis of Biphenyl Derivatives
It is a key intermediate for preparing a wide range of biphenyl-containing compounds. These derivatives find applications in areas such as liquid crystals, organic light-emitting diodes (OLEDs), and as ligands in catalysis.
Research and Development
3-Biphenylmagnesium bromide is employed in academic and industrial research laboratories for novel synthetic methodology development and the exploration of new chemical entities. Its specific reactivity profile aids in targeted molecular design.
| Molecular weight | 257.41 |
|---|---|
| Empirical formula | C12H9BrMg |
| Density | 0.972 g/mL at 25 °C |
| Concentration | 0.5 M in THF |
Hazard statements
- H225Highly flammable liquid and vapour
- H319Causes serious eye irritation
- H335May cause respiratory irritation
- H351Suspected of causing cancer
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P261Avoid breathing dust, fume, gas or vapours
- P281Use personal protective equipment as required
- P305IF IN EYES
| Flash point | -20 - -15 °C / -4 - 5 °F |
|---|---|
| Transport (UN / ADR) | UN 2924 8(3) / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,Xn |
| Risk statements (R) | 11-19-36/37-40 |
| Safety statements (S) | 16-26-36/37 |
| Supplemental hazards | May form explosive peroxides. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-Biphenylmagnesium bromide used for?
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3-Biphenylmagnesium bromide is primarily used as a Grignard reagent in organic synthesis for introducing the biphenyl group into molecules, and for the preparation of various biphenyl derivatives used in materials science and pharmaceutical research.
What is the CAS number and formula for 3-Biphenylmagnesium bromide?
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The CAS number for 3-Biphenylmagnesium bromide is 103068-18-4. Its empirical formula is C12H9BrMg.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 3-Biphenylmagnesium bromide at a concentration of 0.5 M in THF. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
What are the safety considerations when handling 3-Biphenylmagnesium bromide?
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3-Biphenylmagnesium bromide is a flammable liquid and vapour (H225), causes serious eye irritation (H319), and may cause respiratory irritation (H335). It is also suspected of causing cancer (H351) and may form explosive peroxides. Handle with appropriate personal protective equipment in a well-ventilated area, away from ignition sources, and follow all safety guidelines. Refer to the Safety Data Sheet (SDS) for full details.
How is 3-Biphenylmagnesium bromide packed, shipped, and exported?
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3-Biphenylmagnesium bromide is packed according to UN 2924 (Flammable liquid, corrosive, n.o.s.) regulations, classified under Packing Group II. TSS is an experienced global exporter of chemicals, adhering to all international shipping and customs requirements.
How can I request a sample or quote for 3-Biphenylmagnesium bromide?
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Please contact our sales department via the website or email to request a quotation or a sample of 3-Biphenylmagnesium bromide.
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