3-Biphenylboronic acid
3-Biphenylboronic acid (CAS 5122-95-2) is an organoboron compound with the formula C6H5C6H4B(OH)2 and a molecular weight of 198.03 g/mol. It is primarily used as a biological reagent and a reactant in various chemical synthesis applications. This compound is valuable in research for its role in developing chemosensors and evaluating pharmacological activities, particularly as potential fatty acid amide hydrolase inhibitors.
- IUPAC
- (3-Phenylphenyl)boronic acid,3-(Dihydroxyboryl)-1,1′-biphenyl,3-Phenylbenzeneboronic acid
- Synonyms
- (3-Phenylphenyl)boronic acid3-(Dihydroxyboryl)-1,1′-biphenyl3-Phenylbenzeneboronic acid

Biological Reagent
Utilised as a boronate-assisted fluorogenic chemosensor for biological research applications. It plays a role in the development of novel detection and imaging tools in biological systems.
Pharmacological Evaluation
Investigated for its pharmacological activity, specifically as a potential inhibitor of fatty acid amide hydrolase (FAAH). This research contributes to the understanding of lipid signalling pathways.
Chemical Synthesis - Coupling Reactions
Serves as a reactant in various coupling reactions, including those with potassium cyanate, quinones, and fluorous-tagged N-hydroxyphthalimide. These reactions are fundamental in organic synthesis.
Chemical Synthesis - C-H Arylation
Employed in the direct C-H arylation of electron-deficient heterocycles, a significant transformation in modern organic chemistry for constructing complex molecular architectures.
| Molecular weight | 198.03 |
|---|---|
| Linear formula | C6H5C6H4B(OH)2 |
| Application | Biological reagent used as a boronate-assisted fluorogenic chemosensor1Evaluated for pharmacological activity as fatty acid amide hydrolase inhibitors2Reactant involved in:• Coupling with potassium cyanate3, quinones4, or fluorous tagged N-hydroxyphthalimide5• Direct C-H arylation of electron-deficient heterocycles6 |
| Melting point | 193-198 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-Biphenylboronic acid used for?
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3-Biphenylboronic acid is used as a biological reagent, a boronate-assisted fluorogenic chemosensor, and a reactant in chemical synthesis, including coupling reactions and direct C-H arylation. It is also evaluated for pharmacological activity as fatty acid amide hydrolase inhibitors.
What is the CAS number and chemical formula for 3-Biphenylboronic acid?
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The CAS number is 5122-95-2, and the chemical formula is C6H5C6H4B(OH)2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 3-Biphenylboronic acid typically as a research or technical grade material. We do not represent it as USP, BP, EP, or other pharmacopoeial grades unless explicitly stated in the product documentation.
What are the safety precautions for handling 3-Biphenylboronic acid?
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When handling 3-Biphenylboronic acid, it is essential to use appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter should be used if airborne exposure is possible. Refer to the safety data sheet for comprehensive handling information.
Is 3-Biphenylboronic acid a controlled substance?
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Based on the provided data, 3-Biphenylboronic acid is not listed as a controlled substance.
How is 3-Biphenylboronic acid shipped and exported?
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3-Biphenylboronic acid is carefully packed to ensure safe transit and is available for export globally by Tech Serve Solutions, a specialist supplier since 1998.
How can I request a quote or sample of 3-Biphenylboronic acid?
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To request a quote or a sample of 3-Biphenylboronic acid, please contact the Tech Serve Solutions sales team through our website or by phone.
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