3-Amino-5-fluoropyridine
3-Amino-5-fluoropyridine (CAS: 210169-05-4) is a fluorinated pyridine building block with the molecular formula C5H5FN2 and a molecular weight of 112.11 g/mol. This compound serves as a key intermediate in chemical synthesis, particularly in the development of novel pharmaceutical agents. Its structure, featuring both an amine and a fluorine substituent on the pyridine ring, makes it valuable for creating complex organic molecules with specific biological activities.
- IUPAC
- (5-Fluoropyridin-3-yl)amine,3-Amino-5-fluoropyridine,5-Fluoropyridin-3-amine
- Synonyms
- (5-Fluoropyridin-3-yl)amine5-Fluoropyridin-3-amine

Pharmaceutical Intermediate
Utilised in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates. Its fluoropyridine core is incorporated into molecules designed to modulate biological pathways.
Chemical Synthesis Reagent
Serves as a versatile building block for organic chemists in the construction of complex heterocyclic compounds. It is particularly useful in medicinal chemistry research for structure-activity relationship (SAR) studies.
Precursor for Nonpeptide Inhibitors
Reported as a reactant in the preparation of nonpeptide inhibitors, specifically mentioned in relation to the measles virus entry process.
| Molecular weight | 112.11 |
|---|---|
| Empirical formula | C5H5FN2 |
| Application | Reactant for:• Preparation of nonpeptide inhibitors of measles virus entry1 |
| Melting point | 85-89 °C |

Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Water hazard class (WGK, DE) | 3 |
|---|---|
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-36/37/38 |
| Safety statements (S) | 26-36/37 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-Amino-5-fluoropyridine used for?
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3-Amino-5-fluoropyridine is primarily used as a building block in chemical synthesis, notably for the preparation of nonpeptide inhibitors and in the development of novel pharmaceutical agents.
What are the CAS number and formula for 3-Amino-5-fluoropyridine?
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The CAS number for 3-Amino-5-fluoropyridine is 210169-05-4, and its empirical formula is C5H5FN2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 3-Amino-5-fluoropyridine with a purity of 85-89 °C (Melting Point). TSS does not represent this product as USP, BP, or EP grade.
What are the safety and handling precautions for 3-Amino-5-fluoropyridine?
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3-Amino-5-fluoropyridine is classified as a Warning substance. It is harmful if swallowed (H302), causes skin irritation (H315), causes serious eye irritation (H319), and may cause respiratory irritation (H335). Appropriate personal protective equipment, including gloves, eye protection, and respiratory protection, should be used. Ensure adequate ventilation.
How is 3-Amino-5-fluoropyridine packed and shipped?
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3-Amino-5-fluoropyridine is carefully packed to ensure safe transit and is available for global export by Tech Serve Solutions.
How can I request a quote or sample of 3-Amino-5-fluoropyridine?
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To request a quote or sample of 3-Amino-5-fluoropyridine, please contact the Tech Serve Solutions sales team through our website or by phone.
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