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3-Amino-1,2,4-triazole-5-thiol

CAS 16691-43-3C2H4N4SChemical Synthesis

3-Amino-1,2,4-triazole-5-thiol (CAS: 16691-43-3) is a heterocyclic organic compound with the molecular formula C2H4N4S and a molecular weight of 116.14 g/mol. It functions as a key building block in chemical synthesis, particularly for preparing triazole derivatives. Its applications extend to studying corrosion inhibition and developing advanced sensor technologies.

IUPAC
3-Amino-5-mercapto-1,2,4-triazole
Synonyms
16691-43-3C2H4N4S3-Amino-5-mercapto-1,2,4-triazole
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3-Amino-1,2,4-triazole-5-thiol (C2H4N4S) — chemical structure, CAS 16691-43-3; Chemistry, fine chemical supplied by Tech Serve Solutions
Building BlocksChemical SynthesisHeterocyclic Building BlocksTriazoles
01 /Applications

Corrosion Inhibition Studies

This compound has been utilised in research to investigate the inhibition of iron corrosion in saline environments. It serves as a component in studying the effectiveness of certain inhibitors at low concentrations.

Sensor Development

3-Amino-1,2,4-triazole-5-thiol is employed in the preparation of sophisticated sensing materials. Specifically, it has been used in the development of surface-enhanced Raman scattering (SERS) based pH nano- and microsensors utilising silver nanoparticles.

Heterocyclic Synthesis

As a functionalised triazole, it serves as a valuable precursor and building block in organic synthesis for constructing more complex heterocyclic molecules, relevant in medicinal chemistry and materials science.

02 /Properties
Molecular weight116.14
Empirical formulaC2H4N4S
Assay95%
Solubilitywater: soluble25 mg/mL, clear, faintly yellow to yellow
Application3-Amino-1,2,4-triazole-5-thiol was used to study the inhibition of corrosion of iron in 3.5% NaCl solutions by low concentrations of ATT and 1,1′-thiocarbonyldiimidazole1. It was used to prepare surface-enhanced Raman scattering based pH nano- and microsensor using silver nanoparticles2.
Melting point>300 °C(lit.)
03 /Safety & handling
GHS hazard pictogram: Harmful / irritant (GHS07)
Harmful / irritant
Warning

Hazard statements

  • H315Causes skin irritation
  • H319Causes serious eye irritation
  • H335May cause respiratory irritation

Precautionary statements

  • P261Avoid breathing dust, fume, gas or vapours
  • P305IF IN EYES
Protective equipmentdust mask type N95 (US), Eyeshields, Gloves
Water hazard class (WGK, DE)3
Hazard codes (EU)Xi
Risk statements (R)36/37/38
Safety statements (S)26-36

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
16691-43-3
MDL number
MFCD00005231
PubChem substance
24848461
Beilstein registry
112404
05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is 3-Amino-1,2,4-triazole-5-thiol used for?

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3-Amino-1,2,4-triazole-5-thiol is used in research for studying corrosion inhibition of iron in saline solutions and in the preparation of sensors, such as surface-enhanced Raman scattering (SERS) based pH nanosensors.

What is the CAS number and formula for 3-Amino-1,2,4-triazole-5-thiol?

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The CAS number is 16691-43-3 and the empirical formula is C2H4N4S.

What grade and purity does Tech Serve Solutions supply?

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Tech Serve Solutions supplies 3-Amino-1,2,4-triazole-5-thiol with an assay of 95%. This product is not represented as USP, BP, EP, or other pharmacopoeia grades.

How should 3-Amino-1,2,4-triazole-5-thiol be handled safely?

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According to GHS classifications, this compound is a warning substance and may cause skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). Appropriate personal protective equipment, including a dust mask (N95), eyeshields, and gloves, should be used. Ensure adequate ventilation and avoid breathing dust.

How is 3-Amino-1,2,4-triazole-5-thiol packed and shipped?

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Products are carefully packed according to international shipping regulations and are exported globally by Tech Serve Solutions.

How can I request a sample or quote for 3-Amino-1,2,4-triazole-5-thiol?

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Please contact our sales team via the website or direct email to request a quotation or sample of 3-Amino-1,2,4-triazole-5-thiol.

Need 3-Amino-1,2,4-triazole-5-thiol in a specific grade or volume?