3-Acetyl-2,5-dichlorothiophene
3-Acetyl-2,5-dichlorothiophene (CAS: 36157-40-1) is a halogenated heterocyclic compound with the molecular formula C6H4Cl2OS and a molecular weight of 195.07 g/mol. This thiophene derivative serves as a versatile building block in organic synthesis. It is primarily employed in the chemical and pharmaceutical industries for the development of novel compounds and complex molecular structures. Its dichlorinated thiophene core offers specific reactivity for further functionalization.
- IUPAC
- 2,5-Dichloro-3-thienyl methyl ketone
- Synonyms
- 2,5-Dichloro-3-thienyl methyl ketone

Organic Synthesis Intermediate
3-Acetyl-2,5-dichlorothiophene is a key intermediate in the synthesis of more complex organic molecules. Its distinct structural features, including the acetyl group and chlorine substituents on the thiophene ring, allow for targeted chemical modifications.
Pharmaceutical Research
This compound is utilized in pharmaceutical research and development for the creation of novel drug candidates. Its heterocyclic structure can be incorporated into molecules designed to interact with biological targets.
Material Science
As a halogenated heterocycle, it may find applications in material science, contributing to the development of functional materials with specific electronic or optical properties.
| Molecular weight | 195.07 |
|---|---|
| Empirical formula | C6H4Cl2OS |
| Assay | 98% |
| Melting point | 37-40 °C(lit.) |

Hazard statements
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H315Causes skin irritation
- H319Causes serious eye irritation
- H332Harmful if inhaled
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Flash point | 113 °C / 235.4 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 20/21/22-36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-Acetyl-2,5-dichlorothiophene used for?
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3-Acetyl-2,5-dichlorothiophene is used as a versatile building block in organic synthesis, particularly in pharmaceutical research and potentially in material science for developing novel compounds.
What are the CAS number and formula for 3-Acetyl-2,5-dichlorothiophene?
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The CAS number is 36157-40-1 and the empirical formula is C6H4Cl2OS.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 3-Acetyl-2,5-dichlorothiophene with an assay of 98%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should 3-Acetyl-2,5-dichlorothiophene be handled?
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Handling requires appropriate personal protective equipment, including a dust mask type N95 (US), eyeshields, and gloves. It is classified as harmful if swallowed, in contact with skin, or if inhaled, and causes skin and eye irritation, and respiratory irritation (H302, H312, H315, H319, H332, H335).
How is 3-Acetyl-2,5-dichlorothiophene packed and shipped?
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Tech Serve Solutions exports fine chemicals globally. Packing and shipping adhere to international regulations for hazardous materials. Specific packing details can be provided upon request.
How can I request a quote or sample for 3-Acetyl-2,5-dichlorothiophene?
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To request a quote or sample, please use the contact form on our website or email our sales department, providing your full contact details and the product CAS number (36157-40-1).
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