3,5-Dichloro-2,4,6-trifluoropyridine
3,5-Dichloro-2,4,6-trifluoropyridine (CAS: 1737-93-5, C5Cl2F3N) is a fluorinated heterocyclic compound with a molecular weight of 201.96 g/mol. Supplied at 98% purity, this chemical serves as a valuable building block in organic synthesis, particularly in the development of specialised molecules. Its applications are primarily within research and development laboratories, contributing to advancements in chemical and pharmaceutical innovation.
- Synonyms
- 3,5-Dichloro-2,4,6-trifluoropyridine6-trifluoropyridine1737-93-5C5Cl2F3N
Affinity Gel Preparation
3,5-Dichloro-2,4,6-trifluoropyridine has been utilised in the synthesis of affinity gels. Specifically, it played a role in the preparation of Avid AL, an affinity gel employed for the purification of immunoglobulin G.
Fluorinated Heterocyclic Synthesis
As a fluorinated building block, this pyridine derivative is a key intermediate for introducing trifluoropyridine moieties into more complex organic structures. This is crucial for modulating the properties of target molecules in medicinal chemistry and materials science.
Chemical Research and Development
This compound is frequently employed in academic and industrial research settings. Its reactivity and specific structural features make it a useful reagent for exploring novel synthetic pathways and creating new chemical entities.
| Molecular weight | 201.96 |
|---|---|
| Empirical formula | C5Cl2F3N |
| Assay | 98% |
| Boiling point | 159-160 °C(lit.) |
| Density | 1.622 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.478(lit.) |
| Application | 3,5-Dichloro-2,4,6-trifluoropyridine has been used in the preparation of Avid AL, an affinity gel designed for the purification of immunoglobulin G1. |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H330Fatal if inhaled
- H335May cause respiratory irritation
Precautionary statements
- P260Do not breathe dust, fume, gas, mist, vapours or spray
- P284Wear respiratory protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 113 °C / 235.4 °F |
| Transport (UN / ADR) | UN 3382 6.1/PG 1 |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T+ |
| Risk statements (R) | 26-36/37/38 |
| Safety statements (S) | 26-28-36/37-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3,5-Dichloro-2,4,6-trifluoropyridine used for?
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3,5-Dichloro-2,4,6-trifluoropyridine is primarily used as a building block in organic synthesis, including the preparation of affinity gels like Avid AL for immunoglobulin G purification, and in the broader development of fluorinated heterocyclic compounds for research and specialised applications.
What is the CAS number and molecular formula for 3,5-Dichloro-2,4,6-trifluoropyridine?
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The CAS number for 3,5-Dichloro-2,4,6-trifluoropyridine is 1737-93-5, and its molecular formula is C5Cl2F3N.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 3,5-Dichloro-2,4,6-trifluoropyridine with an assay of 98%. This product is intended for research and laboratory use and is not represented as USP, BP, EP, or other pharmacopoeia grades.
How should 3,5-Dichloro-2,4,6-trifluoropyridine be handled?
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Handling requires significant precautions due to its hazardous nature. It is classified as Danger with H315 (Causes skin irritation), H319 (Causes serious eye irritation), H330 (Fatal if inhaled), and H335 (May cause respiratory irritation). Appropriate personal protective equipment, including eyeshields, a full-face respirator (US), gloves, and a multi-purpose combination respirator cartridge or ABEK type filter, is essential. Ensure adequate ventilation and follow strict safety protocols.
How is this chemical packed, shipped, and exported?
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3,5-Dichloro-2,4,6-trifluoropyridine is packed, shipped, and exported in compliance with all relevant transportation regulations for hazardous materials, including UN 3382, Hazard Class 6.1, Packing Group I.
How can I request a quote or sample?
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To request a quote or a sample of 3,5-Dichloro-2,4,6-trifluoropyridine, please contact our sales team through the website or by phone. Provide your specific requirements, including quantity and destination.
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