3-[[4′-(Trifluoromethoxy)phenoxy]methyl]phenylboronic acid
3-[[4′-(Trifluoromethoxy)phenoxy]methyl]phenylboronic acid (CAS: 849062-06-2) is an organoboron compound with the molecular formula C14H12BF3O4 and a molecular weight of 312.05 g/mol. This aryl boronic acid derivative is primarily utilised as a building block in organic synthesis, particularly in cross-coupling reactions. It is an important intermediate for the development of complex organic molecules within the pharmaceutical and materials science sectors.
![3-[[4′-(Trifluoromethoxy)phenoxy]methyl]phenylboronic acid (C14H12BF3O4) — chemical structure, CAS 849062-06-2; Chemistry, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F849062-06-2.png&w=3840&q=75)
Organic Synthesis Intermediate
This compound serves as a versatile reagent in Suzuki-Miyaura cross-coupling reactions, enabling the formation of new carbon-carbon bonds. Its structure makes it valuable for introducing complex aryl and phenoxy motifs into target molecules.
Pharmaceutical Research
As a functionalised boronic acid, it is employed in the synthesis of novel pharmaceutical intermediates and active pharmaceutical ingredients (APIs). Its unique trifluoromethoxy substituent can influence pharmacokinetic properties.
Materials Science
This boronic acid can be incorporated into the design of advanced materials, such as organic light-emitting diodes (OLEDs) or polymers, where its electronic and structural properties are advantageous.
| Molecular weight | 312.05 |
|---|---|
| Empirical formula | C14H12BF3O4 |
| Boiling point | 118-127 °C(lit.) |
| Melting point | 118-127 °C |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
- H413May cause long-lasting harmful effects to aquatic life
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-[[4′-(Trifluoromethoxy)phenoxy]methyl]phenylboronic acid used for?
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3-[[4′-(Trifluoromethoxy)phenoxy]methyl]phenylboronic acid is primarily used as a building block in organic synthesis, particularly for cross-coupling reactions in pharmaceutical research and materials science.
What are the CAS number and molecular formula for this compound?
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The CAS number is 849062-06-2, and the molecular formula is C14H12BF3O4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product for research and development purposes. The specific assay and purity will be detailed on the Certificate of Analysis provided with your order. We do not represent this product as USP, BP, or EP grade.
How should 3-[[4′-(Trifluoromethoxy)phenoxy]methyl]phenylboronic acid be handled safely?
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This compound is a Warning material, causing skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). It may also cause long lasting harmful effects to aquatic life (H413). Handle with appropriate personal protective equipment, including a dust mask (N95), eyeshields, and gloves, in a well-ventilated area. Avoid dust formation and inhalation.
How is this chemical packed and exported by TSS?
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Tech Serve Solutions ensures secure and compliant packaging for international export, adhering to all relevant regulations for chemical shipments.
How can I request a sample or quote for this product?
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To request a sample or a quotation, please use the contact form on our website or email our sales department directly, referencing the product name and CAS number.
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