3,4-(Methylenedioxy)aniline
3,4-(Methylenedioxy)aniline (CAS: 14268-66-7) is a nitrogen-containing organic compound with the molecular formula C7H7NO2. As a fine chemical and building block, it serves as a key intermediate in chemical synthesis. This amine derivative is primarily utilised in research and development for the creation of more complex molecules and speciality chemicals, contributing to advancements in various scientific fields. Its distinct chemical structure makes it a valuable component in organic chemistry.
- IUPAC
- 5-Amino-1,3-benzodioxole
- Synonyms
- 5-Amino-1,3-benzodioxole

Organic Synthesis Intermediate
3,4-(Methylenedioxy)aniline is employed as a fundamental building block in complex organic syntheses. Its reactive amine group allows for diverse chemical transformations, facilitating the construction of novel molecular architectures for research purposes.
Pharmaceutical Research
This compound can be utilised in the exploration of new pharmaceutical agents. Its structure may be incorporated into potential drug candidates for further study and development in medicinal chemistry laboratories.
Speciality Chemical Development
As a versatile chemical intermediate, 3,4-(Methylenedioxy)aniline finds application in the development of speciality chemicals. It is used in syntheses requiring its specific methylenedioxy and aniline functionalities.
| Molecular weight | 137.14 |
|---|---|
| Empirical formula | C7H7NO2 |
| Assay | 97% |
| Boiling point | 144 °C/16 mmHg(lit.) |
| Application | 3,4-(Methylenedioxy)aniline was used in the synthesis of γ-glutamylanilides1. |
| Melting point | 39-41 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Flash point | 143 °C / 289.4 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3,4-(Methylenedioxy)aniline used for?
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3,4-(Methylenedioxy)aniline is primarily used as a building block and intermediate in organic synthesis, particularly in research and development for creating new molecules and speciality chemicals. It has been noted for its use in the synthesis of γ-glutamylanilides.
What are the CAS number and molecular formula for 3,4-(Methylenedioxy)aniline?
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The CAS number for 3,4-(Methylenedioxy)aniline is 14268-66-7, and its molecular formula is C7H7NO2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 3,4-(Methylenedioxy)aniline with an assay of 97%. We do not represent this product as USP, BP, EP, or pharmacopoeia grade.
How should 3,4-(Methylenedioxy)aniline be handled safely?
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3,4-(Methylenedioxy)aniline is a Warning substance that causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Use a dust mask type N95, safety eyeshields, and gloves. Ensure good ventilation, avoid breathing dust, and wash hands thoroughly after handling. Follow precautionary statements P261 and P305 + P351 + P338.
Can Tech Serve Solutions export 3,4-(Methylenedioxy)aniline internationally?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including 3,4-(Methylenedioxy)aniline, adhering to all necessary international shipping regulations.
How can I request a quote or sample for 3,4-(Methylenedioxy)aniline?
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To request a quote or sample for 3,4-(Methylenedioxy)aniline, please contact our sales team through the TSS website or your designated account manager.
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