3′,4′-Difluoroacetophenone
3′,4′-Difluoroacetophenone (CAS: 369-33-5), with the linear formula F₂C₆H₃COCH₃ and a molecular weight of 156.13 g/mol, is a fluorinated organic compound. It serves as a valuable building block in organic synthesis. Its unique difluorinated aromatic structure makes it suitable for the development of novel chemical entities in research and development settings. Available from TSS with an assay of 97%, it is a key intermediate for various chemical processes.
- Synonyms
- F2C6H3COCH3
Chemical Synthesis Intermediate
3′,4′-Difluoroacetophenone is employed as a crucial intermediate in the synthesis of more complex organic molecules. Its fluorinated phenyl ketone structure allows for diverse chemical transformations.
Research and Development
This compound is utilised in research laboratories for exploring new synthetic pathways and developing novel materials or active pharmaceutical ingredients. The presence of fluorine atoms can significantly alter the properties of the final compounds.
Building Block for Fluorinated Compounds
As an aryl fluorinated building block, it is instrumental in introducing difluorinated phenyl moieties into target structures. This is particularly relevant in the design of pharmaceuticals and agrochemicals where fluorine incorporation can enhance efficacy or metabolic stability.
| Molecular weight | 156.13 |
|---|---|
| Linear formula | F2C6H3COCH3 |
| Assay | 97% |
| Boiling point | 94-95 °C/13 mmHg(lit.) |
| Density | 1.246 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.4916(lit.) |
| Application | 3′,4′-Difluoroacetophenone may be used in chemical synthesis. |
| Melting point | 19-20 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 75 °C / 167 °F |
| Transport (UN / ADR) | NA 1993 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3′,4′-Difluoroacetophenone used for?
+
3′,4′-Difluoroacetophenone is primarily used as an intermediate in chemical synthesis and in research and development for creating new organic molecules, particularly those incorporating fluorinated aromatic structures.
What is the CAS number and molecular formula for 3′,4′-Difluoroacetophenone?
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The CAS number for 3′,4′-Difluoroacetophenone is 369-33-5, and its linear formula is F₂C₆H₃COCH₃.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 3′,4′-Difluoroacetophenone with an assay of 97%. This is a research or technical grade material and is not represented as USP, BP, or EP grade.
What are the safety and handling recommendations for 3′,4′-Difluoroacetophenone?
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3′,4′-Difluoroacetophenone is classified with Warning (GHS07) signal word and carries hazard statements H315 (Causes skin irritation), H319 (Causes serious eye irritation), and H335 (May cause respiratory irritation). Appropriate personal protective equipment, including eyeshields, gloves, and suitable respiratory protection, should be used. Follow P261 and P305 + P351 + P338 precautionary statements.
How is 3′,4′-Difluoroacetophenone packed, shipped, and exported?
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3′,4′-Difluoroacetophenone is packed and shipped according to standard chemical handling procedures, adhering to regulations for international export. Specific packaging details can be provided upon request.
How can I request a quote or sample of 3′,4′-Difluoroacetophenone?
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To request a quote or a sample of 3′,4′-Difluoroacetophenone, please contact the TSS sales team via our website or direct inquiry channels.
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