3,4,5-Trimethoxyphenylboronic acid
3,4,5-Trimethoxyphenylboronic acid (CAS: 182163-96-8), with the molecular formula C9H13BO5 and a molecular weight of 212.01 g/mol, is a trisubstituted aryl boronic acid. It serves as a valuable building block in organic synthesis, particularly in Suzuki-Miyaura cross-coupling reactions. Its unique trimethoxy substitution pattern makes it useful for introducing specific structural motifs in the development of complex molecules across various chemical research fields.
- IUPAC
- 3,4,5-Trimethoxybenzeneboronic acid
- Synonyms
- 182163-96-8C9H13BO53,4,5-Trimethoxybenzeneboronic acid

Organic Synthesis Building Block
3,4,5-Trimethoxyphenylboronic acid is employed as a key intermediate in the synthesis of diverse organic compounds. Its aryl boronic acid functionality readily participates in palladium-catalyzed cross-coupling reactions, facilitating the formation of new carbon-carbon bonds.
Pharmaceutical Intermediate Development
This compound is utilised in the research and development of novel pharmaceutical agents. The trimethoxyphenyl moiety can be incorporated into drug candidates, potentially influencing their pharmacological properties and efficacy.
Materials Science Research
Researchers in materials science may use 3,4,5-Trimethoxyphenylboronic acid for the synthesis of specialised organic materials. Its structure can be a precursor to functional polymers or organic electronic components.
| Molecular weight | 212.01 |
|---|---|
| Empirical formula | C9H13BO5 |
| Assay | ≥95.0% |
| Melting point | >230 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3,4,5-Trimethoxyphenylboronic acid used for?
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3,4,5-Trimethoxyphenylboronic acid is primarily used as a building block in organic synthesis, particularly for the development of pharmaceutical intermediates and novel organic materials via reactions like the Suzuki-Miyaura cross-coupling.
What is the CAS number and molecular formula for 3,4,5-Trimethoxyphenylboronic acid?
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The CAS number is 182163-96-8, and the molecular formula is C9H13BO5.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 3,4,5-Trimethoxyphenylboronic acid with an assay of ≥95.0%. We do not represent this product as USP, BP, EP, or for nutraceutical, food, or pharmaceutical use, and it is intended for research and laboratory applications.
What are the safety and handling precautions for 3,4,5-Trimethoxyphenylboronic acid?
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This compound has a WGK Germany rating of 3, indicating it is hazardous. Handling requires appropriate personal protective equipment, including eyeshields, gloves, and a suitable respirator filter (type N95 or P1). Refer to the Safety Data Sheet for comprehensive handling guidelines.
How is 3,4,5-Trimethoxyphenylboronic acid typically packed, shipped, and exported?
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3,4,5-Trimethoxyphenylboronic acid is carefully packed according to international shipping regulations for chemicals and is available for global export by Tech Serve Solutions.
How can I request a quote or sample for 3,4,5-Trimethoxyphenylboronic acid?
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To request a quote or a sample of 3,4,5-Trimethoxyphenylboronic acid, please contact our sales team through the website or by phone.
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