3,4,5-Trimethoxybenzoyl chloride
3,4,5-Trimethoxybenzoyl chloride (CAS 4521-61-3) is a reactive organic acid halide with the linear formula (CH3O)3C6H2COCl and a molecular weight of 230.64 g/mol. This compound serves as a valuable building block in organic synthesis, particularly in the preparation of esters and amides. It is often employed in the development of pharmaceuticals and other fine chemicals due to its functional group, enabling diverse chemical transformations.
- Synonyms
- 4521-61-3
Pharmaceutical Intermediate Synthesis
3,4,5-Trimethoxybenzoyl chloride is utilised in the multi-step synthesis of active pharmaceutical ingredients (APIs). Its acylating ability allows for the introduction of the trimethoxybenzoyl moiety into complex molecular structures.
Organic Building Block
As a functionalised aromatic compound, it acts as a versatile building block for creating more complex organic molecules. It is commonly used in academic and industrial research laboratories for novel compound development.
Chemical Research and Development
This chemical finds application in various research areas requiring the specific structural features of the trimethoxybenzoyl group. It facilitates the exploration of new chemical reactions and material properties.
| Molecular weight | 230.64 |
|---|---|
| Linear formula | (CH3O)3C6H2COCl |
| Assay | 98% |
| Boiling point | 185 °C/18 mmHg(lit.) |
| Storage temperature | 2-8°C |
| Melting point | 81-84 °C(lit.) |
Hazard statements
- H314Causes severe skin burns and eye damage
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 3261 8 / PGII |
| Water hazard class (WGK, DE) | 1 |
| Hazard codes (EU) | C |
| Risk statements (R) | 14-34-37 |
| Safety statements (S) | 26-36/37/39-45 |
| Supplemental hazards | Reacts violently with water. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3,4,5-Trimethoxybenzoyl chloride primarily used for?
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3,4,5-Trimethoxybenzoyl chloride is primarily used as a building block in organic synthesis, particularly for the preparation of pharmaceuticals and other fine chemicals, by facilitating the introduction of the trimethoxybenzoyl group.
What is the CAS number and formula for 3,4,5-Trimethoxybenzoyl chloride?
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The CAS number is 4521-61-3 and the linear formula is (CH3O)3C6H2COCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 3,4,5-Trimethoxybenzoyl chloride with an assay of 98%. We do not represent this product as USP, BP, or EP grade.
How should 3,4,5-Trimethoxybenzoyl chloride be handled safely?
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3,4,5-Trimethoxybenzoyl chloride is corrosive and a severe irritant. It reacts violently with water. Handle with appropriate personal protective equipment, including eyeshields, faceshields, gloves, and respiratory protection. Ensure adequate ventilation and avoid contact with moisture.
How is this chemical shipped and exported?
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3,4,5-Trimethoxybenzoyl chloride is shipped and exported according to international regulations for hazardous materials. It is classified under UN 3261, Hazard Class 8, Packing Group II.
How can I request a sample or quote for 3,4,5-Trimethoxybenzoyl chloride?
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To request a sample or quote, please contact the Tech Serve Solutions sales team through our website or by phone, referencing the product name and CAS number.
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