3,3′,5′-Triiodo-L-thyronine
3,3′,5′-Triiodo-L-thyronine (CAS 5817-39-0), a synthetic iodothyronine analogue, is a critical biochemical reagent. With a molecular weight of 650.97 g/mol and empirical formula C15H12I3NO4, it serves as an essential tool in biochemical research and diagnostics. Its primary applications lie in thyroid hormone research and related metabolic studies.
- IUPAC
- Reverse T3,rT(3)
- Synonyms
- 5817-39-0C15H12I3NO4Reverse T3rT(3)

Thyroid Hormone Research
3,3′,5′-Triiodo-L-thyronine is extensively used in studies investigating the structure-activity relationships of thyroid hormones and their metabolic pathways. It aids in understanding the mechanisms of thyroid hormone action at the cellular level.
Biochemical Assays
This compound functions as a standard or reference material in various biochemical assays, particularly those related to thyroid function tests and the study of iodothyronine deiodinase activity.
Endocrinology Studies
It is employed in endocrinological research to probe the complexities of the hypothalamic-pituitary-thyroid axis. Researchers utilise it to investigate hormone receptor binding and signalling pathways.
| Molecular weight | 650.97 |
|---|---|
| Empirical formula | C15H12I3NO4 |
| Storage temperature | −20°C |

Hazard statements
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H332Harmful if inhaled
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 20/21/22 |
| Safety statements (S) | 36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3,3′,5′-Triiodo-L-thyronine used for?
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3,3′,5′-Triiodo-L-thyronine is primarily used in biochemical research, particularly for studies involving thyroid hormone analogues, metabolic pathways, and endocrinology research. It serves as a valuable reagent in biochemical assays and diagnostics.
What is the CAS number and formula for 3,3′,5′-Triiodo-L-thyronine?
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The CAS number for 3,3′,5′-Triiodo-L-thyronine is 5817-39-0, and its empirical formula is C15H12I3NO4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 3,3′,5′-Triiodo-L-thyronine primarily for research and laboratory use. The specific assay and purity details are available on the product's Certificate of Analysis; we do not represent this product as USP, BP, or EP grade unless explicitly stated.
How should 3,3′,5′-Triiodo-L-thyronine be handled safely?
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Handle 3,3′,5′-Triiodo-L-thyronine with appropriate personal protective equipment, including a dust mask (type N95 US recommended), eyeshields, and gloves. Avoid inhalation, ingestion, and skin contact, as it is harmful if swallowed, in contact with skin, or inhaled (H302-H312-H332).
How is 3,3′,5′-Triiodo-L-thyronine shipped and exported?
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Tech Serve Solutions is experienced in the global supply and export of chemicals. 3,3′,5′-Triiodo-L-thyronine is typically stored at -20°C and shipped according to international regulations for chemical substances.
How can I request a sample or quote for 3,3′,5′-Triiodo-L-thyronine?
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To request a sample or a quote for 3,3′,5′-Triiodo-L-thyronine, please contact our sales department through the website or via email, specifying your requirements.
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