3-(2-Aminoethyl)-5-((4-ethoxyphenyl)methylene)-2,4-thiazolidinedione hydrochloride
3-(2-Aminoethyl)-5-((4-ethoxyphenyl)methylene)-2,4-thiazolidinedione hydrochloride (CAS 294675-79-9) is a selective extracellular signal-regulated kinase (ERK) docking domain inhibitor. With a molecular weight of 328.81, this compound is valuable in research settings for studying the role of ERK pathways. Its applications are primarily focused on cellular biology and the investigation of neurological conditions, such as traumatic brain injuries, where ERK signalling is implicated.
- IUPAC
- Erk Inhibitor
- Synonyms
- C14H16N2O3S · HCl
ERK Pathway Inhibition
This compound acts as an extracellular signal-regulated kinase (ERK) docking domain inhibitor. It is utilized in biochemical assays and cell-based studies to specifically block ERK signalling pathways, enabling researchers to elucidate the functions of ERK in various cellular processes.
Neuroscience Research
ERK inhibitors, including this compound, have been employed in the study of traumatic brain injuries. Research focuses on understanding the involvement of ERK pathways in neuroprotection, neuroinflammation, and functional recovery following TBI.
Cell Biology Investigations
As a bioactive small molecule, it serves as a tool in cell biology to investigate signal transduction pathways. Its specificity for ERK docking domains allows for detailed exploration of cellular responses to stimuli that activate the MAPK/ERK cascade.
| Molecular weight | 328.81 |
|---|---|
| Empirical formula | C14H16N2O3S · HCl |
| Assay | ≥98% (HPLC) |
| Solubility | DMSO: ≥4 mg/mL |
| Storage temperature | 2-8°C |
| Application | 3-(2-Aminoethyl)-5-((4-ethoxyphenyl)methylene)-2,4-thiazolidinedione is an extracellular signal-regulated kinase (ERK) docking domain inhibitor. ERK inhibitors have been used to study traumatic brain injuries. |
| Storage Condition | desiccatedunder inert gas |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-(2-Aminoethyl)-5-((4-ethoxyphenyl)methylene)-2,4-thiazolidinedione hydrochloride used for?
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This compound is used as an extracellular signal-regulated kinase (ERK) docking domain inhibitor, primarily for research in cell biology and neuroscience, particularly in studies related to traumatic brain injuries.
What is the CAS number and formula for this compound?
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The CAS number for the free base is 294675-79-9, and the empirical formula (hill notation) for the hydrochloride salt is C14H16N2O3S · HCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this compound with a purity of ≥98% (HPLC). This is a research-grade chemical and TSS does not represent it as USP, BP, EP, or other pharmacopoeia grades.
How should 3-(2-Aminoethyl)-5-((4-ethoxyphenyl)methylene)-2,4-thiazolidinedione hydrochloride be handled and stored?
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According to the safety data, this compound has a WGK Germany rating of 3, indicating it is hazardous. It should be stored desiccated under inert gas at 2-8°C. Consult the Safety Data Sheet (SDS) for comprehensive handling and safety information.
Is this compound available for export?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including this compound.
How can I request a sample or quote?
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Please contact our sales team through the website or by phone to request a sample or a detailed quotation for this product.
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