3-(1,3-Dioxolan-2-yl)phenylboronic acid pinacol ester
3-(1,3-Dioxolan-2-yl)phenylboronic acid pinacol ester (CAS: 1257648-34-2) is an organoboron compound with the molecular formula C15H21BO4 and a molecular weight of 276.14. This aryl boronate ester is a valuable building block in organic synthesis, particularly for cross-coupling reactions. Its structure incorporates a protected aldehyde equivalent, making it useful for introducing functionalised phenyl groups in complex molecule construction.
- IUPAC
- 2-(3-(1,3-dioxolan-2-yl)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
- Synonyms
- 2-(3-(1,3-dioxolan-2-yl)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
Suzuki-Miyaura Coupling Reactions
This compound serves as a key coupling partner in Suzuki-Miyaura reactions, facilitating the formation of carbon-carbon bonds. It is used to introduce the 3-(1,3-dioxolan-2-yl)phenyl moiety into various organic frameworks.
Organic Synthesis Intermediate
As an aryl boronate ester, it is a versatile intermediate in the synthesis of complex organic molecules, including pharmaceuticals and advanced materials. The pinacol ester provides stability and ease of handling.
Building Block for Heterocycles
This reagent can be employed in the synthesis of diverse heterocyclic compounds. The dioxolane group acts as a protected aldehyde, which can be deprotected and further functionalised post-coupling.
| Molecular weight | 276.14 |
|---|---|
| Empirical formula | C15H21BO4 |
| Melting point | 45-50 °C |
| Flash point | >110 °C / >230 °F |
|---|---|
| Water hazard class (WGK, DE) | 1 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-(1,3-Dioxolan-2-yl)phenylboronic acid pinacol ester used for?
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3-(1,3-Dioxolan-2-yl)phenylboronic acid pinacol ester is primarily used as a building block in organic synthesis, particularly for Suzuki-Miyaura cross-coupling reactions to introduce functionalised phenyl groups into complex molecules.
What are the CAS number and formula for this compound?
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The CAS number is 1257648-34-2, and the empirical formula is C15H21BO4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this compound for research and chemical synthesis purposes. Please refer to the Certificate of Analysis for specific assay and purity details. It is not supplied as USP, BP, EP, or pharmaceutical grade.
What are the safety and handling precautions for this chemical?
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This compound is classified with GHS hazard pictograms. It is combustible with a high flash point (>110 °C). Handle with appropriate personal protective equipment in a well-ventilated area to avoid exposure. Refer to the Safety Data Sheet for detailed information.
How is this product packed, shipped, and exported?
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Tech Serve Solutions packs and exports chemicals in compliance with all relevant international shipping regulations. Packaging is designed to maintain product integrity during transit.
How can I request a sample or quote for 3-(1,3-Dioxolan-2-yl)phenylboronic acid pinacol ester?
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To request a sample or a quotation, please contact our sales team through the website or by calling our office, providing the product name and CAS number.
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