3-(1,1,2,2-Tetrafluoroethoxy)benzaldehyde
3-(1,1,2,2-Tetrafluoroethoxy)benzaldehyde (CAS 35295-35-3) is an organic fluorinated building block with the molecular formula C9H6F4O2 and a molecular weight of 222.14 g/mol. This liquid compound, featuring a tetrafluoroethoxy group attached to a benzaldehyde core, serves as a versatile intermediate in organic synthesis. Its specific structure makes it valuable for introducing fluorinated moieties into more complex molecules, particularly in the development of pharmaceuticals and advanced materials.
- Synonyms
- 3-(1,1,2,2-Tetrafluoroethoxy)benzaldehyde2-(Tetrafluoroethoxy)benzaldehydeF2CHCF2OC6H4CHO

Organic Synthesis Intermediate
This compound is utilised as a key building block in the synthesis of novel organic molecules. The presence of the aldehyde functional group allows for a variety of chemical transformations, while the fluorinated ether substituent can impart unique physicochemical properties to the final products.
Pharmaceutical Research
It serves as a precursor in the development of potential drug candidates. Fluorinated organic compounds are often explored in medicinal chemistry due to fluorine's ability to modulate metabolic stability, lipophilicity, and binding affinity of active pharmaceutical ingredients.
Materials Science
The unique electronic and physical properties conferred by the tetrafluoroethoxy group can be leveraged in the design of specialised materials. Applications may include polymers, liquid crystals, or other advanced functional materials.
| Molecular weight | 222.14 |
|---|---|
| Linear formula | F2CHCF2OC6H4CHO |
| Assay | 95% |
| Form | liquid |
| Density | 1.393 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.454(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 102 °C / 215.6 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-(1,1,2,2-Tetrafluoroethoxy)benzaldehyde used for?
+
3-(1,1,2,2-Tetrafluoroethoxy)benzaldehyde is primarily used as an intermediate and building block in organic synthesis, particularly in pharmaceutical research and materials science due to its fluorinated structure.
What is the CAS number and molecular formula for 3-(1,1,2,2-Tetrafluoroethoxy)benzaldehyde?
+
The CAS number is 35295-35-3 and the molecular formula is C9H6F4O2.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies 3-(1,1,2,2-Tetrafluoroethoxy)benzaldehyde with a minimum purity of 95%. This product is not represented as USP, BP, EP, or any other pharmacopoeia grade.
How should 3-(1,1,2,2-Tetrafluoroethoxy)benzaldehyde be handled safely?
+
This compound is classified as a Warning with hazards H315 (causes skin irritation), H319 (causes serious eye irritation), and H335 (may cause respiratory irritation). Appropriate personal protective equipment, including eyeshields and gloves, should be worn. Work should be conducted in a well-ventilated area or with suitable respiratory protection.
Is 3-(1,1,2,2-Tetrafluoroethoxy)benzaldehyde packed and shipped internationally?
+
Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 3-(1,1,2,2-Tetrafluoroethoxy)benzaldehyde, and handles international shipping.
How can I request a sample or a quote for 3-(1,1,2,2-Tetrafluoroethoxy)benzaldehyde?
+
To request a sample or a quote, please contact our sales department through the website or by calling us directly. Provide the product name and CAS number (35295-35-3) for prompt service.
▶ Related products

1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis

1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more

3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis

3-Methyl-1,5-pentanediol
Chemical Synthesis

3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis