2-(tert-Butoxycarbonyloxy)phenylboronic acid pinacol ester
2-(tert-Butoxycarbonyloxy)phenylboronic acid pinacol ester (CAS 480424-71-3) is an organoboron compound with a molecular weight of 320.19 g/mol. It features a phenylboronic acid pinacol ester moiety protected by a tert-butoxycarbonyloxy group. This compound serves as a valuable building block in organic synthesis, particularly in cross-coupling reactions, enabling the formation of carbon-carbon bonds in complex molecule construction.
- IUPAC
- tert-Butyl-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenylcarbonate,tert-Butyl 2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl carbonate
- Synonyms
- tert-Butyl-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenylcarbonatetert-Butyl 2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl carbonate

Suzuki-Miyaura Coupling Reagent
This compound is frequently employed as a coupling partner in Suzuki-Miyaura reactions. It facilitates the synthesis of biaryl compounds, which are prevalent structural motifs in pharmaceuticals and advanced materials.
Organic Synthesis Intermediate
As a versatile intermediate, it allows for the introduction of a substituted phenylboronic acid ester into various organic frameworks. Its protected hydroxyl group offers selective reaction pathways.
Pharmaceutical Research and Development
The compound is utilised in the discovery and development of new pharmaceutical agents. Its application aids in the creation of novel molecular architectures with potential therapeutic properties.
Materials Science
It can be incorporated into the synthesis of functional materials, such as organic light-emitting diodes (OLEDs) or polymers, where specific electronic or optical properties are desired.
| Molecular weight | 320.19 |
|---|---|
| Linear formula | (CH3)3COCOOC6H4BO2C2(CH3)4 |
| Assay | 97% |
| Melting point | 73-77 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-(tert-Butoxycarbonyloxy)phenylboronic acid pinacol ester used for?
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This compound is primarily used as a building block in organic synthesis, especially for Suzuki-Miyaura coupling reactions to form carbon-carbon bonds and create complex molecules for pharmaceutical research and materials science.
What are the CAS number and formula for this product?
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The CAS number is 480424-71-3. The linear formula is (CH3)3COCOOC6H4BO2C2(CH3)4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product at a minimum purity of 97%. We do not represent this product as USP, BP, or EP grade.
What are the main safety hazards associated with this chemical?
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Users should wear eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. It is classified with a WGK of 3 in Germany, indicating a high hazard to water.
How is this product packed and shipped by TSS?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, pharmaceutical intermediates, and laboratory reagents, adhering to all necessary regulations for safe international transport.
How can I request a sample or a quote for 2-(tert-Butoxycarbonyloxy)phenylboronic acid pinacol ester?
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Please contact our sales team via the website or by phone to request a sample or a quotation for this product.
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