2-Nitro-N-methylbenzylamine
2-Nitro-N-methylbenzylamine (CAS 56222-08-3), with the molecular formula O₂NC₆H₄CH₂NHCH₃ and a molecular weight of 166.18 g/mol, is a valuable organic building block. This compound is primarily utilised as a reactant in the synthesis of various biologically active molecules, including calmodulin kinase II inhibitors, AP2238 derivatives, and cholinesterase inhibitors. It serves as a key intermediate in diverse chemical synthesis pathways.
- IUPAC
- N-Methyl-2-nitrobenzenemethanamine
- Synonyms
- N-Methyl-2-nitrobenzenemethanamine
Synthesis of Calmodulin Kinase II Inhibitors
2-Nitro-N-methylbenzylamine serves as a crucial reactant in the development of specific calmodulin kinase II inhibitors, contributing to research in cellular signalling pathways.
Intermediate for AP2238 Derivatives
This chemical is employed in the synthesis of AP2238 derivatives, highlighting its utility in creating complex molecular structures for pharmacological investigation.
Precursor for Cholinesterase Inhibitors
The compound acts as a precursor in the synthesis of cholinesterase inhibitors, relevant for developing agents that modulate enzyme activity.
Azole Antifungal Agent Synthesis
2-Nitro-N-methylbenzylamine is a key component in the synthetic routes leading to azole antifungal agents, important in medicinal chemistry.
| Molecular weight | 166.18 |
|---|---|
| Linear formula | O2NC6H4CH2NHCH3 |
| Boiling point | 110-120 °C/3 mmHg(lit.) |
| Density | 1.1750 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.5580(lit.) |
| Application | Reactant involved in the synthesis of biologically active molecules including:• Calmodulin kinase II inhibitors1• AP2238 derivatives2• Cholinesterase inhibitors3• Azole antifungal agents4 |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Nitro-N-methylbenzylamine used for?
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2-Nitro-N-methylbenzylamine is used as a reactant in the synthesis of biologically active molecules such as calmodulin kinase II inhibitors, AP2238 derivatives, cholinesterase inhibitors, and azole antifungal agents.
What is the CAS number and formula for 2-Nitro-N-methylbenzylamine?
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The CAS number for 2-Nitro-N-methylbenzylamine is 56222-08-3, and its linear formula is O₂NC₆H₄CH₂NHCH₃.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Nitro-N-methylbenzylamine primarily as a reagent for chemical synthesis and research. The specific assay or grade will be detailed on the Certificate of Analysis. TSS does not represent this product as USP, BP, EP, or for nutraceutical/food use.
How should 2-Nitro-N-methylbenzylamine be handled safely?
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Handle 2-Nitro-N-methylbenzylamine with appropriate personal protective equipment, including eyeshields, gloves, and a dust mask (type N95 US recommended). Ensure good ventilation and avoid breathing dust. It is classified with Warning signal word, and H315, H319, H335 hazard statements (causes skin irritation, serious eye irritation, and may cause respiratory irritation).
How is 2-Nitro-N-methylbenzylamine packed and exported?
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2-Nitro-N-methylbenzylamine is carefully packed according to industry standards for safe handling, storage, and international export, ensuring product integrity during transit.
How can I request a sample or quote for 2-Nitro-N-methylbenzylamine?
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To request a sample or a quote for 2-Nitro-N-methylbenzylamine, please contact the TSS sales team directly through our website or by phone.
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