2-Methoxythiophenol
2-Methoxythiophenol (CAS: 7217-59-6), with the chemical formula CH3OC6H4SH and a molecular weight of 140.20 g/mol, is a notable organic compound. This aromatic thiol serves as a valuable building block in chemical synthesis, particularly in the creation of complex organic molecules and intermediates. Its characteristic sulfur and methoxy groups enable diverse chemical transformations, making it a compound of interest for researchers and industrial chemists.
- IUPAC
- 2-Methoxybenzenethiol,2-Mercaptoanisole,Thioguaiacol
Synthesis of Oxazolidinone Derivatives
2-Methoxythiophenol has been employed in the synthesis of chiral oxazolidinone derivatives, such as (4S)-N-[(2S)-2-methy-3-(2-methoxyphenylthio)propanoyl]-4-phenyloxazolidin-2-one. This application highlights its utility in constructing complex, stereochemically defined molecules.
Intermediate for Heterocyclic Compounds
The compound acts as a key intermediate in the preparation of fused heterocyclic systems. For instance, it has been used in the synthesis of 2-(4-fluorophenyl)-6-(2-methoxyphenylsulfanyl)imidazo[1,2-a]pyridine, demonstrating its role in building diverse ring structures.
Preparation of Benzoic Acid Derivatives
2-Methoxythiophenol is a precursor for the synthesis of substituted benzoic acids. Its use in preparing 2-(2-methoxyphenylsulfanyl)benzoic acid showcases its utility in introducing sulfur-containing aryl moieties onto carboxylic acid frameworks.
| Molecular weight | 140.20 |
|---|---|
| Linear formula | CH3OC6H4SH |
| Assay | 97% |
| Boiling point | 99 °C/8 mmHg(lit.) |
| Density | 1.152 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.591(lit.) |
| Application | 2-Methoxythiophenol was used in the synthesis of:• (4S)-N-[(2S)-2-methy-3-(2-methoxyphenylthio)propanoyl]-4-phenyloxazolidin-2-one1• 2-(4-fluorophenyl)-6-(2-methoxyphenylsulfanyl)imidazo[1,2-a]pyridine2• 2-(2-methoxyphenylsulfanyl)benzoic acid3 |
Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 96 °C / 204.8 °F |
| Transport (UN / ADR) | UN 3334 |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-36/37/38 |
| Safety statements (S) | 26-36/37 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Methoxythiophenol used for?
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2-Methoxythiophenol is used as a building block in chemical synthesis, particularly for creating complex organic molecules, heterocyclic compounds, and substituted benzoic acids.
What are the CAS number and chemical formula for 2-Methoxythiophenol?
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The CAS number is 7217-59-6 and the chemical formula is CH3OC6H4SH.
What grade and purity does Tech Serve Solutions supply for 2-Methoxythiophenol?
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Tech Serve Solutions supplies 2-Methoxythiophenol with a purity of 97%. This product is suitable for research and chemical synthesis purposes; TSS does not represent it as USP, BP, or EP grade.
How should 2-Methoxythiophenol be handled safely?
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2-Methoxythiophenol is classified with warning signal word and hazard statements including H302 (Harmful if swallowed), H315 (Causes skin irritation), H319 (Causes serious eye irritation), and H335 (May cause respiratory irritation). Appropriate personal protective equipment, including eyeshields, gloves, and respiratory protection, should be used. Handle in a well-ventilated area.
Is 2-Methoxythiophenol packed, shipped, or exported by TSS?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 2-Methoxythiophenol, and handles its packing and export.
How can I request a sample or quote for 2-Methoxythiophenol?
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To request a sample or a quote for 2-Methoxythiophenol, please contact our sales department through the website or by phone, providing your specific requirements.
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