2-Methoxypyridine-5-boronic acid pinacol ester

CAS 445264-61-9C12H18BNO3Chemical Synthesis

2-Methoxypyridine-5-boronic acid pinacol ester (CAS 445264-61-9; C12H18BNO3) is a valuable organoboron compound with a molecular weight of 235.09 g/mol. It serves as a crucial building block in organic synthesis, particularly in cross-coupling reactions. This heteroaryl boronate ester facilitates the formation of carbon-carbon bonds, enabling the construction of complex molecular architectures relevant in pharmaceutical research and material science.

IUPAC: 2-Methoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine,2-Methoxy-5-pyridineboronic acid pinacol ester
Synonyms: 2-Methoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine2-Methoxy-5-pyridineboronic acid pinacol ester

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2-Methoxypyridine-5-boronic acid pinacol ester (C12H18BNO3) — chemical structure, CAS 445264-61-9; Chemistry, fine chemical supplied by Tech Serve Solutions

Boronate EstersChemical SynthesisHeteroaryl Boronate EstersOrganometallic Reagents

01 /Applications

Organic Synthesis Intermediate

Utilised as a key reagent in Suzuki-Miyaura cross-coupling reactions to introduce the 2-methoxypyridin-5-yl moiety into diverse organic molecules.

Pharmaceutical Research

A versatile building block for the synthesis of novel drug candidates and biologically active compounds, contributing to medicinal chemistry efforts.

Material Science

Employed in the development of functional materials and organic electronics where specific pyridine-based structural units are required.

02 /Properties

Molecular weight	235.09
Empirical formula	C12H18BNO3
Assay	97%
Melting point	47-51 °C(lit.)

03 /Safety & handling

GHS hazard pictogram: Harmful / irritant (GHS07) — Harmful / irritant

Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation

Precautionary statements

P305IF IN EYES

Protective equipment	dust mask type N95 (US), Eyeshields, Gloves
Flash point	102 °C / 215.6 °F
Water hazard class (WGK, DE)	3
Hazard codes (EU)	Xi
Risk statements (R)	36/38
Safety statements (S)	26

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

445264-61-9

MDL number

MFCD05663858

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is 2-Methoxypyridine-5-boronic acid pinacol ester used for?

It is primarily used as an intermediate in organic synthesis, particularly for Suzuki-Miyaura cross-coupling reactions, and in research for pharmaceuticals and material science.

What is the CAS number and molecular formula?

The CAS number is 445264-61-9, and the molecular formula is C12H18BNO3.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies this product at a minimum purity of 97%. We do not represent this product as USP, BP, or EP grade.

How should 2-Methoxypyridine-5-boronic acid pinacol ester be handled?

This compound is a Warning hazard (H315-H319), causing skin and serious eye irritation. Handle with appropriate personal protective equipment, including a dust mask (N95 US), eyeshields, and gloves. Ensure good ventilation.