2-Methoxybenzylmagnesium chloride solution
2-Methoxybenzylmagnesium chloride solution (CAS: 480438-46-8) is a valuable organometallic reagent with the linear formula CH3OC6H4CH2MgCl. It functions as a versatile building block in organic synthesis, particularly for introducing the 2-methoxybenzyl group into various molecular structures. Its applications span pharmaceutical research and fine chemical manufacturing, leveraging its reactivity in carbon-carbon bond formation.

Organic Synthesis Reagent
This Grignard reagent is employed in complex organic syntheses to facilitate nucleophilic addition reactions. It is crucial for constructing carbon frameworks in the development of novel compounds.
Pharmaceutical Intermediate Production
Utilised in the synthesis pathways for pharmaceutical intermediates, where precise introduction of the 2-methoxybenzyl moiety is required for target molecule construction.
Fine Chemical Manufacturing
Serves as a key reagent in the manufacturing of specialised fine chemicals, enabling efficient functionalisation of organic molecules.
| Molecular weight | 180.91 |
|---|---|
| Linear formula | CH3OC6H4CH2MgCl |
| Boiling point | 65 °C |
| Density | 0.910 g/mL at 25 °C |
| Concentration | 0.25 M in THF |
| Storage temperature | 2-8°C |




Hazard statements
- H225Highly flammable liquid and vapour
- H314Causes severe skin burns and eye damage
- H335May cause respiratory irritation
- H351Suspected of causing cancer
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Flash point | -17 °C / 1.4 °F |
|---|---|
| Transport (UN / ADR) | UN 2924 8(3) / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,C |
| Risk statements (R) | 11-14-19-34-37-40 |
| Safety statements (S) | 16-26-36/37/39-45 |
| Supplemental hazards | May form explosive peroxides., Reacts violently with water. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Methoxybenzylmagnesium chloride solution used for?
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This compound is primarily used as a reagent in organic synthesis, particularly for introducing the 2-methoxybenzyl group into molecules, finding applications in pharmaceutical intermediate production and fine chemical manufacturing.
What is the CAS number and formula for 2-Methoxybenzylmagnesium chloride solution?
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The CAS number is 480438-46-8, and its linear formula is CH3OC6H4CH2MgCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Methoxybenzylmagnesium chloride solution at a concentration of 0.25 M in THF. We do not represent this product as USP, BP, or EP grade.
How should 2-Methoxybenzylmagnesium chloride solution be handled safely?
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This is a highly flammable liquid and vapour (H225), causes severe skin burns and eye damage (H314), and may cause respiratory irritation (H335). It may also cause drowsiness or dizziness. It reacts violently with water and can form explosive peroxides. Handle with extreme caution in a well-ventilated area, wearing appropriate protective equipment, and avoid contact with water and ignition sources.
Is 2-Methoxybenzylmagnesium chloride solution a controlled substance?
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The provided data does not indicate that 2-Methoxybenzylmagnesium chloride solution is a controlled substance.
How is 2-Methoxybenzylmagnesium chloride solution packed, shipped, and exported?
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Tech Serve Solutions exports chemicals globally, ensuring compliance with international shipping regulations. Specific packaging details will be provided upon inquiry.
How can I request a sample or quote for 2-Methoxybenzylmagnesium chloride solution?
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Please contact our sales team via the website or direct email to request a sample or quote for 2-Methoxybenzylmagnesium chloride solution.
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