2-Isobutyl-3-methoxypyrazine
2-Isobutyl-3-methoxypyrazine (CAS: 24683-00-9, C9H14N2O) is a heterocyclic organic compound with a molecular weight of 166.22 g/mol. This pyrazine derivative is primarily utilised as a building block in chemical synthesis. Its notable application involves its use as a model odorant molecule in electrochemical assays designed for detecting other odorant molecules, particularly in research involving olfactory receptors.

Model Odorant in Electrochemical Assays
2-Isobutyl-3-methoxypyrazine serves as a key model odorant in the development and validation of electrochemical assays. These assays are specifically designed for the sensitive detection of various odorant molecules, often utilising protein interactions.
Research in Olfactory Studies
The compound's well-defined olfactory properties make it valuable in research focused on understanding the mechanisms of olfaction. It is employed in studies investigating odorant-binding proteins, such as rat odorant-binding protein (rOBP3), to probe molecular recognition processes.
Building Block for Chemical Synthesis
As a heterocyclic building block, 2-Isobutyl-3-methoxypyrazine is a useful intermediate in organic synthesis. It can be incorporated into more complex molecular structures within research and development settings.
| Molecular weight | 166.22 |
|---|---|
| Empirical formula | C9H14N2O |
| Assay | 99% |
| Density | 0.99 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.49(lit.) |
| Application | 2-Isobutyl-3-methoxypyrazine has been employed as a model odorant molecule during an electrochemical assay for the detection of odorant molecules based on a rat odorant-binding protein (rOBP3)1. |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 80 °C / 176 °F |
| Transport (UN / ADR) | NA 1993 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Isobutyl-3-methoxypyrazine used for?
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2-Isobutyl-3-methoxypyrazine is used as a model odorant molecule in electrochemical assays for detecting odorant molecules and as a building block in chemical synthesis, particularly in research related to olfactory studies.
What are the CAS number and formula for 2-Isobutyl-3-methoxypyrazine?
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The CAS number for 2-Isobutyl-3-methoxypyrazine is 24683-00-9, and its empirical formula is C9H14N2O.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Isobutyl-3-methoxypyrazine with a minimum assay of 99%. This product is not supplied as USP, BP, EP, or any pharmacopoeia grade.
How should 2-Isobutyl-3-methoxypyrazine be handled?
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Handling requires appropriate personal protective equipment, including eyeshields, gloves, and a suitable respirator (e.g., multi-purpose combination respirator cartridge or type ABEK respirator filter). It is classified with GHS07 signal word Warning, with hazard statements H315 (causes skin irritation), H319 (causes serious eye irritation), and H335 (may cause respiratory irritation).
Is 2-Isobutyl-3-methoxypyrazine available for export?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including 2-Isobutyl-3-methoxypyrazine.
How can I request a sample or quote for 2-Isobutyl-3-methoxypyrazine?
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To request a sample or a quote, please contact the Tech Serve Solutions sales team through the website or by phone, providing the product name and CAS number.
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