2-Iodophenol
2-Iodophenol (CAS 533-58-4) is a halogenated phenol used as a versatile organic building block in chemical synthesis. Its structure, featuring both a hydroxyl group and an iodine atom on a benzene ring, allows for diverse chemical transformations. This compound is primarily utilized in academic and industrial research for creating complex organic molecules, including various heterocyclic compounds with potential pharmaceutical applications.

Synthesis of Enantiomerically Pure Carbinols
Used in the synthesis of aryl 2-benzofuranyl and aryl 2-indolyl carbinols, achieving high enantiomeric purity for these complex structures.
Preparation of Dihydrobenzofurans
Serves as a precursor in the synthesis of 3,3-disubstituted-2,3-dihydrobenzofurans, a class of organic compounds.
Organic Synthesis Intermediate
A valuable building block for constructing more complex organic molecules in research and development settings.
| Molecular weight | 220.01 |
|---|---|
| Linear formula | IC6H4OH |
| Assay | 98% |
| Boiling point | 186-187 °C/160 mmHg(lit.) |
| Density | 1.947 g/mL at 25 °C(lit.) |
| Application | 2-Iodophenol was used in the synthesis of:• aryl 2-benzofuranyl and aryl 2-indolyl carbinols of high enantiomeric purity1• 3,3-disubstituted-2,3-dihydrobenzofurans2 |
| Melting point | 37-40 °C(lit.) |

Hazard statements
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H315Causes skin irritation
- H319Causes serious eye irritation
- H332Harmful if inhaled
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Flash point | 113 °C / 235.4 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 20/21/22-36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Iodophenol used for?
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2-Iodophenol is primarily used as a building block in organic synthesis for the preparation of various complex organic molecules, including specific types of carbinols and dihydrobenzofurans.
What is the CAS number and formula for 2-Iodophenol?
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The CAS number for 2-Iodophenol is 533-58-4, and its linear formula is IC6H4OH.
What is the grade/purity of 2-Iodophenol supplied by TSS?
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Tech Serve Solutions supplies 2-Iodophenol with a purity of 98%.
How is 2-Iodophenol classified regarding hazards?
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2-Iodophenol is classified with a Warning signal word. It is harmful if swallowed (H302), harmful in contact with skin (H312), causes skin irritation (H315), causes serious eye irritation (H319), and harmful if inhaled (H332), may cause respiratory irritation (H335).
How is 2-Iodophenol packed and shipped?
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2-Iodophenol is typically packed and shipped in compliance with relevant regulations for hazardous materials. Specific packaging and shipping details can be provided upon request.
How can I request a quote for 2-Iodophenol?
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To request a quote for 2-Iodophenol, please contact our sales department with your specific quantity requirements.
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