2-Iodo-3-hydroxypyridine
2-Iodo-3-hydroxypyridine (CAS 40263-57-8), with the molecular formula C5H4INO and a molecular weight of 221.00 g/mol, is a key heterocyclic building block. This compound is primarily utilised in chemical synthesis, particularly in the creation of more complex molecules within pharmaceutical research and development. Its structure, featuring both a pyridine ring and an iodine atom, makes it a versatile intermediate for various coupling reactions and functional group transformations.
- IUPAC
- 2-Iodo-3-pyridinol

Pharmaceutical Intermediate
2-Iodo-3-hydroxypyridine serves as a crucial intermediate in the synthesis pathways for novel pharmaceutical agents. Its reactivity allows for the introduction of pyridine moieties into drug candidates, aiding in the development of new therapeutics.
Organic Synthesis Reagent
As a functionalised pyridine, this compound is valuable in organic chemistry research for constructing complex molecular architectures. It is employed in various coupling reactions and as a precursor for diverse heterocyclic compounds.
Material Science Research
The unique electronic and structural properties of halogenated pyridines can be leveraged in material science for developing novel organic materials with specific optoelectronic or functional characteristics.
| Molecular weight | 221.00 |
|---|---|
| Empirical formula | C5H4INO |
| Assay | 97% |
| Melting point | 196-200 °C (D) |


Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H318Causes serious eye damage
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-37/38-41 |
| Safety statements (S) | 26-39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Iodo-3-hydroxypyridine used for?
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2-Iodo-3-hydroxypyridine is primarily used as a building block and intermediate in organic synthesis, particularly in pharmaceutical research and development for creating complex heterocyclic molecules.
What is the CAS number and formula for 2-Iodo-3-hydroxypyridine?
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The CAS number is 40263-57-8 and the molecular formula is C5H4INO.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Iodo-3-hydroxypyridine with a minimum assay of 97%. This product is intended for research and chemical synthesis purposes and is not represented as USP, BP, EP, or pharmacopoeia grade.
How should 2-Iodo-3-hydroxypyridine be handled safely?
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Handling requires appropriate personal protective equipment, including a dust mask (type N95 US recommended), eyeshields, and gloves. It is classified as Danger with hazards including H302 (Harmful if swallowed), H315 (Causes skin irritation), H318 (Causes serious eye damage), and H335 (May cause respiratory irritation). Ensure good ventilation.
How is 2-Iodo-3-hydroxypyridine packed and shipped?
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Products are carefully packed according to industry standards to ensure safe transit and are exported globally by Tech Serve Solutions.
How can I request a quote or sample?
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Please visit the Tech Serve Solutions website or contact our sales team to request a quotation or inquire about obtaining a sample of 2-Iodo-3-hydroxypyridine.
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