2-Hydroxy-5-(trifluoromethyl)pyridine
2-Hydroxy-5-(trifluoromethyl)pyridine (CAS: 33252-63-0, C6H4F3NO) is a valuable trifluoromethylated pyridine derivative. With a molecular weight of 163.10 g/mol, it serves as a key building block in organic synthesis. Its structure makes it suitable for introducing the trifluoromethylpyridine moiety into more complex molecules, finding utility in the development of pharmaceuticals and agrochemicals.
- IUPAC
- 5-(Trifluoromethyl)-2-pyridinol
- Synonyms
- 5-(Trifluoromethyl)-2-pyridinol
Pharmaceutical Intermediate
This compound is employed as a building block in the synthesis of active pharmaceutical ingredients (APIs). Its trifluoromethylpyridine structure can impart desirable pharmacokinetic properties to drug candidates.
Agrochemical Development
It is used in the research and development of novel agrochemicals, such as herbicides, insecticides, and fungicides, where the trifluoromethyl group often enhances biological activity.
Organic Synthesis Reagent
As a heterocyclic building block, it facilitates the construction of complex organic molecules through various coupling and functionalization reactions in synthetic chemistry laboratories.
| Molecular weight | 163.10 |
|---|---|
| Empirical formula | C6H4F3NO |
| Assay | 97% |
| Melting point | 145-149 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Hydroxy-5-(trifluoromethyl)pyridine used for?
+
2-Hydroxy-5-(trifluoromethyl)pyridine is primarily used as a building block in organic synthesis, particularly for the development of pharmaceuticals and agrochemicals.
What are the CAS number and chemical formula for this compound?
+
The CAS number is 33252-63-0, and the chemical formula is C6H4F3NO.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies 2-Hydroxy-5-(trifluoromethyl)pyridine with an assay of 97%. We do not represent this product as meeting USP, BP, or EP pharmacopoeial standards.
How should 2-Hydroxy-5-(trifluoromethyl)pyridine be handled?
+
Handle with appropriate personal protective equipment, including a dust mask (type N95 US recommended), eyeshields, and gloves. Avoid breathing dust and ensure adequate ventilation. This compound is a Warning: Causes skin irritation, serious eye irritation, and may cause respiratory irritation (H315-H319-H335).
Can you provide information on its melting point?
+
The melting point of 2-Hydroxy-5-(trifluoromethyl)pyridine is typically between 145-149 °C.
Does Tech Serve Solutions export this chemical?
+
Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including 2-Hydroxy-5-(trifluoromethyl)pyridine.
How can I request a quote or sample?
+
To request a quote or sample, please contact our sales team through the website or provide your inquiry details via email.
▶ Related products
1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis
1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis