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2-Formylphenylboronic acid MIDA ester

CAS 1257651-51-6C12H12BNO5Chemical Synthesis

2-Formylphenylboronic acid MIDA ester (CAS 1257651-51-6), with molecular formula C12H12BNO5 and a molecular weight of 261.04 g/mol, is a key building block in organic synthesis. This MIDA boronate derivative serves as a versatile reagent, particularly valuable in Suzuki-Miyaura cross-coupling reactions. Its stable nature and controlled reactivity make it an excellent choice for constructing complex molecular architectures in pharmaceutical and materials science research.

IUPAC
2-(6-Methyl-4,8-dioxo-1,3,6,2-dioxazaborocan-2-yl)benzaldehyde
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2-Formylphenylboronic acid MIDA ester (C12H12BNO5) — chemical structure, CAS 1257651-51-6; Chemistry, fine chemical supplied by Tech Serve Solutions
AldehydesAryl MIDA BoronatesBuilding BlocksC10-C12Carbonyl CompoundsChemical SynthesisMIDA BoronatesOrganic Building Blocks
01 /Applications

Suzuki-Miyaura Cross-Coupling Reactions

This compound is an effective coupling partner in Suzuki-Miyaura reactions, enabling the formation of carbon-carbon bonds. Its MIDA ester functionality offers improved stability and handling compared to free boronic acids.

Organic Synthesis Building Block

As an aryl MIDA boronate, it functions as a valuable building block for creating diverse organic molecules. It is particularly useful in the synthesis of complex organic compounds and intermediates for drug discovery and fine chemicals.

Aldehyde Functionalised Boronate

The presence of both an aldehyde and a boronate ester group within the same molecule allows for sequential or selective functionalization in multi-step synthetic pathways.

02 /Properties
Molecular weight261.04
Empirical formulaC12H12BNO5
Assay97%
ApplicationSuzuki Cross-Coupling with MIDA Boronates
Melting point224-229 °C
03 /Safety & handling
GHS hazard pictogram: Harmful / irritant (GHS07)
Harmful / irritant
Warning

Hazard statements

  • H302Harmful if swallowed
Protective equipmentdust mask type N95 (US), Eyeshields, Gloves
Water hazard class (WGK, DE)3
Hazard codes (EU)Xn
Risk statements (R)22

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
1257651-51-6
05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is 2-Formylphenylboronic acid MIDA ester primarily used for?

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2-Formylphenylboronic acid MIDA ester is primarily used as a building block in organic synthesis, especially for Suzuki-Miyaura cross-coupling reactions.

What are the CAS number and formula for 2-Formylphenylboronic acid MIDA ester?

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The CAS number is 1257651-51-6, and the molecular formula is C12H12BNO5.

What grade and purity does Tech Serve Solutions supply?

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Tech Serve Solutions supplies 2-Formylphenylboronic acid MIDA ester at an assay of 97%. This product is supplied for research and development purposes and is not represented as USP, BP, EP, or pharmacopoeia grade.

How should 2-Formylphenylboronic acid MIDA ester be handled safely?

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This compound is classified as a Warning (GHS07) with hazard statement H302 (Harmful if swallowed). Safe handling requires wearing a dust mask type N95 (US), eyeshields, and gloves. Ensure adequate ventilation.

How is this chemical packed and shipped?

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2-Formylphenylboronic acid MIDA ester is carefully packed to ensure safe transport and is exported globally by Tech Serve Solutions.

How can I request a quote or sample?

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To request a quote or a sample of 2-Formylphenylboronic acid MIDA ester, please visit the Tech Serve Solutions website or contact our sales team directly.

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