2-Fluoro-4-(methoxycarbonyl)phenylboronic acid pinacol ester
2-Fluoro-4-(methoxycarbonyl)phenylboronic acid pinacol ester (CAS: 603122-79-8; Formula: C14H18BFO4; MW: 280.10) is a specialised aryl boronate ester. It serves as a versatile building block in organic synthesis, particularly within cross-coupling reactions. Its utility is prominent in the development of complex molecules for pharmaceutical research and material science, offering precise functionalisation capabilities for advanced chemical structures.
- IUPAC
- Methyl 3-fluoro-4-(4,4,5,5,-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate
- Synonyms
- Methyl 3-fluoro-4-(4,4,5,5,-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate
Organic Synthesis Intermediate
Utilised in Suzuki-Miyaura cross-coupling reactions to introduce fluorinated aryl moieties. This is crucial for the synthesis of advanced intermediates in medicinal chemistry and material science applications.
Pharmaceutical Research
Serves as a key building block for creating novel drug candidates. Its structure allows for precise modification in the development of active pharmaceutical ingredients (APIs).
Material Science
Incorporated into the synthesis of functional organic materials. Its fluorinated aromatic structure can impart desirable electronic or physical properties to polymers and organic electronics.
| Molecular weight | 280.10 |
|---|---|
| Empirical formula | C14H18BFO4 |
| Assay | 97% |
| Melting point | 66-71 °C |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Water hazard class (WGK, DE) | 3 |
|---|---|
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Fluoro-4-(methoxycarbonyl)phenylboronic acid pinacol ester used for?
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This compound is primarily used as an intermediate in organic synthesis, particularly for cross-coupling reactions like the Suzuki-Miyaura coupling, enabling the construction of complex molecules for pharmaceutical research and material science.
What are the CAS number and formula for this compound?
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The CAS number is 603122-79-8 and the empirical formula (Hill notation) is C14H18BFO4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product at an assay of 97%. We do not represent it as USP, BP, EP or other pharmacopoeial grades.
How should 2-Fluoro-4-(methoxycarbonyl)phenylboronic acid pinacol ester be handled?
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This compound is a warning irritant. Handle with appropriate personal protective equipment (PPE) to avoid skin, eye, and respiratory irritation. Ensure good ventilation. Refer to the Safety Data Sheet (SDS) for detailed handling procedures.
Is this product suitable for export?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals and can arrange shipment worldwide.
How can I request a sample or quote?
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Please contact our sales team via the website or email to request a sample or a formal quotation for 2-Fluoro-4-(methoxycarbonyl)phenylboronic acid pinacol ester.
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